糖和精氨酸通过确保肠内耐受性免疫细胞亚群的功能来促进口服耐受性。
关键词: CP: Immunology CP: Metabolism CX3CR1(+) cells allergy dendritic cells fasting food antigens mTOR signaling metabolic rewiring nutrition oral tolerance regulatory T cells
Mesh : Animals Arginine / metabolism Immune Tolerance T-Lymphocytes, Regulatory / immunology Ovalbumin / immunology Dendritic Cells / immunology metabolism Mice TOR Serine-Threonine Kinases / metabolism Mice, Inbred C57BL Administration, Oral CX3C Chemokine Receptor 1 / metabolism Intestines / immunology Antigens, CD / metabolism Integrin alpha Chains / metabolism Sugars / metabolism Glycolysis Fasting Signal Transduction Intestinal Mucosa / immunology metabolism Female
来 源: DOI:10.1016/j.celrep.2024.114490