Abstract：
Men who have sex with men (MSM) are vulnerable to HIV infection. Although daily oral pre-exposure prophylaxis (PrEP) prevents HIV among MSM, its usage remains low. We conducted virtual in-depth interviews (IDIs) and focus groups (FGs) with Black, Hispanic/Latino, and White MSM consisting of current PrEP users and those aware of but not currently using PrEP. We delved into their preferences regarding six emerging PrEP products: a weekly oral pill, event-driven oral pills, anal douche/enema, anal suppository, long-acting injection, and a skin implant. Our mixed methods analysis involved inductive content analysis of transcripts for thematic identification and calculations of preferences. Among the sample (n = 98), the weekly oral pill emerged as the favored option among both PrEP Users and PrEP Aware IDI participants. Ranking exercises during FGs also corroborated this preference, with the weekly oral pill being most preferred. However, PrEP Users in FGs leaned toward the long-acting injectable. Conversely, the anal suppository and douche/enema were the least preferred products. Overall, participants were open to emerging PrEP products and valued flexibility but expressed concerns about limited protection for products designed solely for receptive sex. Public health practitioners should tailor recommendations based on individuals\' current sexual behaviors and long-term vulnerability to infection.
摘要：
男男性行为者（MSM）容易感染HIV。尽管每天口服暴露前预防（PrEP）可以预防MSM中的HIV，它的使用率仍然很低。我们对布莱克进行了虚拟深度访谈(IDI)和焦点小组(FG)，西班牙裔/拉丁裔,和白色MSM由当前的PrEP用户和那些知道但目前不使用PrEP的用户组成。我们深入研究了他们对六种新兴PrEP产品的偏好：每周口服药丸，事件驱动的口服药丸，肛门冲洗/灌肠,肛门栓剂,长效注射剂,和皮肤植入物。我们的混合方法分析涉及对转录本进行归纳内容分析，以进行主题识别和偏好计算。在样本中(n=98)，每周口服药丸成为PrEP用户和PrEP感知IDI参与者的首选选择.FG期间的排名练习也证实了这一偏好，最优选每周口服避孕药。然而,FGs中的PrEP用户倾向于长效注射剂。相反，肛门栓剂和冲洗/灌肠剂是最不优选的产品.总的来说,参与者对新兴的PrEP产品持开放态度,并重视灵活性,但对仅为接受性设计的产品的保护有限表示担忧.公共卫生从业人员应根据个人当前的性行为和长期感染的脆弱性来制定建议。
