Abstract:
The use of exogenous glucocorticoids is a common cause of Cushing syndrome. We present a case of exogenous Cushing syndrome caused by Binahong: an over-the-counter \'herbal\' supplement. A 54-year-old woman presented with weight gain, joint pain, hypertension and poorly regulated type 2 diabetes mellitus despite the start of semaglutide one year before presentation. Physical examination revealed signs of steroid excess with a moon face and abdominal obesity. Her serum cortisol level and ACTH level were suppressed. Synthetic glucocorticoid screening revealed a positive dexamethason level in the herbal supplement. After stopping the supplement her serum cortisol and dexamethason increased to normal levels. This case emphasizes the importance of awareness for the use of supplements containing hidden glucocorticoids causing Cushing syndrome.
摘要:
使用外源性糖皮质激素是库欣综合征的常见原因。我们介绍了一例由Binahong引起的外源性库欣综合征:一种非处方“草药”补充剂。一名54岁的女性出现体重增加,关节痛,尽管在出现前一年开始服用司马鲁肽,但高血压和2型糖尿病调节不良。体格检查显示,月亮脸和腹部肥胖有类固醇过量的迹象。她的血清皮质醇水平和ACTH水平被抑制。合成糖皮质激素筛查显示草药补充剂中的地塞米松水平呈阳性。停止补充后,她的血清皮质醇和地塞米松增加到正常水平。该病例强调了使用含有隐藏糖皮质激素的补充剂引起库欣综合征的重要性。