PDF(Pubmed)
Abstract：
Cancer genomic services (CGS) can support genetic risk-stratified cancer prevention and treatment. Racial/ethnic minority groups are less likely to access and utilize CGS compared with non-Hispanic Whites. Little research has described characteristics of interventions targeted at CGS among Latinos. This scoping review aimed to (1) describe interventions promoting uptake of CGS among Latinos in the United States and Latin America, (2) describe intervention adaptations for Latino participants, and (3) summarize intervention implementation factors suggested by reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) framework. We conducted a search in English and Spanish of literature published between 2005 and 2022 across PubMed and Latin American and Caribbean Health Sciences Literature databases. Sixteen of 2344 papers met the inclusion criteria of the analysis. Efforts to promote CGS among Latino communities were limited in the US and lower in Latin America. This review highlights the need for in-depth exploration of acculturation-informed interventions and better reporting on implementation factors to enhance their scalability across diverse settings.
摘要：
癌症基因组服务（CGS）可以支持遗传风险分层的癌症预防和治疗。与非西班牙裔白人相比，种族/少数民族群体不太可能获得和利用CGS。很少有研究描述了针对拉丁裔CGS的干预措施的特征。此范围审查旨在（1）描述促进美国和拉丁美洲拉丁美洲人吸收CGS的干预措施，(2)描述拉丁裔参与者的干预适应，(3)总结影响因素，有效性,收养,实施，和维护(RE-AIM)框架。我们在PubMed和拉丁美洲和加勒比健康科学文献数据库中搜索了2005年至2022年之间发表的英文和西班牙文文献。2344篇论文中有16篇符合分析的纳入标准。在拉丁美洲社区中推广CGS的努力在美国受到限制，而在拉丁美洲则较低。这篇综述强调了对文化适应知情干预措施进行深入探索的必要性，并更好地报告实施因素，以增强其在不同环境中的可扩展性。
