PDF(Pubmed)
Abstract：
UNASSIGNED: Landau-Kleffner syndrome (LKS) is a rare epileptic encephalopathy characterized by language regression and abnormal electroencephalogram (EEG) patterns. This case report highlights the importance of early recognition and intervention in LKS, as well as the challenges in diagnosis and management due to its varied clinical manifestations.
UNASSIGNED: An 8-year-old girl presented with delayed speech, suspected hearing loss, and regression in language skills. Diagnostic tests revealed mild sensorineural hearing loss and EEG abnormalities consistent with LKS. The patient underwent speech therapy and received pharmacological treatment with valproic acid, resulting in significant improvements in language function.
UNASSIGNED: This case report provides insights into the typical features of LKS, including language regression and EEG abnormalities. It also highlights uncommon findings such as sensorineural hearing loss and mild intellectual delay. The multidisciplinary approach involving neurology, audiology, speech therapy, and education is crucial in the diagnosis and management of LKS.
UNASSIGNED: Early recognition and intervention, along with tailored pharmacological approaches and a multidisciplinary care approach, are essential in managing LKS. Further research is needed to better understand the pathophysiology, natural history, and optimal treatment of LKS, aiming to improve long-term outcomes for affected children and their families.
UNASSIGNED: An 8-year-old girl presented with delayed speech, suspected hearing loss, and regression in language skills. Diagnostic tests revealed mild sensorineural hearing loss and EEG abnormalities consistent with LKS. The patient underwent speech therapy and received pharmacological treatment with valproic acid, resulting in significant improvements in language function.
UNASSIGNED: This case report provides insights into the typical features of LKS, including language regression and EEG abnormalities. It also highlights uncommon findings such as sensorineural hearing loss and mild intellectual delay. The multidisciplinary approach involving neurology, audiology, speech therapy, and education is crucial in the diagnosis and management of LKS.
UNASSIGNED: Early recognition and intervention, along with tailored pharmacological approaches and a multidisciplinary care approach, are essential in managing LKS. Further research is needed to better understand the pathophysiology, natural history, and optimal treatment of LKS, aiming to improve long-term outcomes for affected children and their families.
摘要：
■Landau-Kleffner综合征（LKS）是一种罕见的癫痫性脑病，其特征是语言回归和异常的脑电图（EEG）模式。本病例报告强调了早期识别和干预LKS的重要性，以及由于其临床表现多样而在诊断和管理方面的挑战。
■一个8岁的女孩出现说话延迟，疑似听力损失,和语言技能的回归。诊断测试显示轻度的感觉神经性听力损失和EEG异常与LKS一致。患者接受了言语治疗，并接受了丙戊酸的药物治疗，导致语言功能的显著改进。
■本病例报告提供了对LKS典型特征的见解，包括语言回归和脑电图异常。它还强调了罕见的发现，如感音神经性听力损失和轻度智力延迟。涉及神经病学的多学科方法，听力学,言语治疗,教育在LKS的诊断和管理中至关重要。
■早期识别和干预，加上量身定制的药理学方法和多学科护理方法，对管理LKS至关重要。需要进一步的研究来更好地了解病理生理学，自然史,以及LKS的最佳治疗方法，旨在改善受影响儿童及其家庭的长期结果。
■一个8岁的女孩出现说话延迟，疑似听力损失,和语言技能的回归。诊断测试显示轻度的感觉神经性听力损失和EEG异常与LKS一致。患者接受了言语治疗，并接受了丙戊酸的药物治疗，导致语言功能的显著改进。
■本病例报告提供了对LKS典型特征的见解，包括语言回归和脑电图异常。它还强调了罕见的发现，如感音神经性听力损失和轻度智力延迟。涉及神经病学的多学科方法，听力学,言语治疗,教育在LKS的诊断和管理中至关重要。
■早期识别和干预，加上量身定制的药理学方法和多学科护理方法，对管理LKS至关重要。需要进一步的研究来更好地了解病理生理学，自然史,以及LKS的最佳治疗方法，旨在改善受影响儿童及其家庭的长期结果。
