Software and Databases for Protein-Protein Docking.

用于蛋白质 - 蛋白质对接的软件和数据库。

• 发表时间: 2024
• 来源期刊: Methods Mol Biol
• DOI: 10.1007/978-1-0716-3985-6_8
• PMID: 38987467
• 文章类型: Journal Article
• 作者列表: Jarończyk M,Abagyan R,Totrov M

关键词: Fast Fourier transform; Monte Carlo; PPI; Protein bioinformatics; Protein databases; Protein–protein docking; Protein–protein interactions; Protein–protein interface

Mesh: Software; Databases, Protein; Molecular Docking Simulation; Protein Interaction Mapping / methods; Proteins / chemistry metabolism; Computational Biology / methods; Protein Binding; Humans

Abstract

Protein-protein interactions (PPIs) provide valuable insights for understanding the principles of biological systems and for elucidating causes of incurable diseases. One of the techniques used for computational prediction of PPIs is protein-protein docking calculations, and a variety of software has been developed. This chapter is a summary of software and databases used for protein-protein docking.

摘要

蛋白质-蛋白质相互作用（PPI）为理解生物系统的原理和阐明无法治愈的疾病的原因提供了有价值的见解。用于PPI计算预测的技术之一是蛋白质-蛋白质对接计算，并开发了各种软件。本章概述了用于蛋白质-蛋白质对接的软件和数据库。