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Abstract：
BACKGROUND: Ticks, as critical vectors of a variety of pathogens, pose a significant public health challenge globally. In Southeast Asia (SEA), ticks are responsible for transmitting a diverse array of pathogens affecting humans and animals. The geographical and ecological diversity of SEA provides a unique environment that supports a wide range of tick species, which complicates the management and study of tick-borne diseases (TBDs).
RESULTS: This article synthesizes findings from the first international symposium on ticks and TBDs in Southeast Asia, held in Phnom Penh on June 22 and 23, 2023. It highlights regional efforts to understand tick ecology and pathogen transmission. This paper proposes to present a summary of the various presentations given during the symposium following 3 main parts. The first one is devoted to the state of knowledge regarding ticks and TBDs in SEA countries, with presentations from 6 different countries, namely Cambodia, Indonesia, Laos, Malaysia, Thailand, and Vietnam. The second part focuses on the development of new research approaches on tick-borne pathogens (TBPs) and TBDs. The last part is a summary of the round table discussion held on the final day, with the aim of defining the most important challenges and recommendations for researches on TBP and TBD in the SEA region.
CONCLUSIONS: Key topics discussed include advancements in diagnostic tools, such as MALDI-TOF MS and proteomics, and the development of sustainable strategies for tick management and disease prevention. The symposium facilitated the exchange of knowledge and collaborative networks among experts from various disciplines, promoting a unified approach to tackling TBDs in the region. The symposium underscored the need for enhanced surveillance, diagnostics, and inter-regional cooperation to manage the threat of TBDs effectively. Recommendations include the establishment of a regional database for tick identification and the expansion of vector competence studies. These initiatives are crucial for developing targeted interventions and understanding the broader implications of climate change and urbanization on the prevalence of TBDs.
RESULTS: This article synthesizes findings from the first international symposium on ticks and TBDs in Southeast Asia, held in Phnom Penh on June 22 and 23, 2023. It highlights regional efforts to understand tick ecology and pathogen transmission. This paper proposes to present a summary of the various presentations given during the symposium following 3 main parts. The first one is devoted to the state of knowledge regarding ticks and TBDs in SEA countries, with presentations from 6 different countries, namely Cambodia, Indonesia, Laos, Malaysia, Thailand, and Vietnam. The second part focuses on the development of new research approaches on tick-borne pathogens (TBPs) and TBDs. The last part is a summary of the round table discussion held on the final day, with the aim of defining the most important challenges and recommendations for researches on TBP and TBD in the SEA region.
CONCLUSIONS: Key topics discussed include advancements in diagnostic tools, such as MALDI-TOF MS and proteomics, and the development of sustainable strategies for tick management and disease prevention. The symposium facilitated the exchange of knowledge and collaborative networks among experts from various disciplines, promoting a unified approach to tackling TBDs in the region. The symposium underscored the need for enhanced surveillance, diagnostics, and inter-regional cooperation to manage the threat of TBDs effectively. Recommendations include the establishment of a regional database for tick identification and the expansion of vector competence studies. These initiatives are crucial for developing targeted interventions and understanding the broader implications of climate change and urbanization on the prevalence of TBDs.
摘要：
背景：滴答，作为各种病原体的关键媒介，在全球范围内构成重大公共卫生挑战。在东南亚（SEA），壁虱负责传播影响人类和动物的各种病原体。SEA的地理和生态多样性提供了一个独特的环境，支持各种各样的蜱物种，这使得蜱传疾病（TBD）的管理和研究复杂化。
结果：本文综合了第一届东南亚蜱和TBD国际研讨会的结果，2023年6月22日和23日在金边举行。它强调了区域努力了解蜱生态和病原体传播。本文建议在以下三个主要部分对研讨会期间的各种演讲进行总结。第一个是专门介绍SEA国家关于蜱和TBD的知识状况，来自6个不同国家的演讲，即柬埔寨,印度尼西亚,老挝,马来西亚,泰国,和越南。第二部分重点介绍了蜱传病原体（TBP）和TBD的新研究方法的开发。最后一部分是最后一天举行的圆桌讨论会的总结,旨在为SEA地区的TBP和TBD研究确定最重要的挑战和建议。
结论：讨论的主要主题包括诊断工具的改进，如MALDI-TOFMS和蛋白质组学，以及制定蜱虫管理和疾病预防的可持续战略。专题讨论会促进了各学科专家之间的知识交流和合作网络，促进统一的方法来解决该地区的TBD。专题讨论会强调需要加强监测，诊断,和区域间合作，以有效管理TBD的威胁。建议包括建立蜱识别区域数据库和扩大媒介能力研究。这些举措对于制定有针对性的干预措施以及了解气候变化和城市化对TBD流行的更广泛影响至关重要。
结果：本文综合了第一届东南亚蜱和TBD国际研讨会的结果，2023年6月22日和23日在金边举行。它强调了区域努力了解蜱生态和病原体传播。本文建议在以下三个主要部分对研讨会期间的各种演讲进行总结。第一个是专门介绍SEA国家关于蜱和TBD的知识状况，来自6个不同国家的演讲，即柬埔寨,印度尼西亚,老挝,马来西亚,泰国,和越南。第二部分重点介绍了蜱传病原体（TBP）和TBD的新研究方法的开发。最后一部分是最后一天举行的圆桌讨论会的总结,旨在为SEA地区的TBP和TBD研究确定最重要的挑战和建议。
结论：讨论的主要主题包括诊断工具的改进，如MALDI-TOFMS和蛋白质组学，以及制定蜱虫管理和疾病预防的可持续战略。专题讨论会促进了各学科专家之间的知识交流和合作网络，促进统一的方法来解决该地区的TBD。专题讨论会强调需要加强监测，诊断,和区域间合作，以有效管理TBD的威胁。建议包括建立蜱识别区域数据库和扩大媒介能力研究。这些举措对于制定有针对性的干预措施以及了解气候变化和城市化对TBD流行的更广泛影响至关重要。
