Abstract：
OBJECTIVE: This study aimed to determine the effect of adrenal mass functionality and different hormone subtypes synthesized by the adrenal masses on laparoscopic adrenalectomy (LA) outcomes.
METHODS: The study included 298 patients, 154 of whom were diagnosed with nonfunctional masses. In the functional group, 33, 62, and 59 patients had Conn syndrome, Cushing\'s syndrome, and pheochromocytoma, respectively. The variables were analyzed between the functional and nonfunctional groups and then compared among functional masses through subgroup analysis.
RESULTS: The incidence of diabetes mellitus, hypertension, and obesity, blood loss, and length of hospital stay (LOH) were significantly higher in the functional group than in the nonfunctional group. In the subgroup analysis, patients with pheochromocytoma had significantly lower body mass index but significantly higher mass size, blood loss, and LOH than the other two groups. A positive correlation was found between mass size and blood loss in patients with pheochromocytoma (p ≤ 0.001, r = 0.761). However, no significant difference in complications was found among the groups.
CONCLUSIONS: In this study, patients with functional adrenal masses had higher comorbidity rates and American Society of Anesthesiologists scores. Moreover, blood loss and LOH were longer on patients with functional adrenal masses who underwent LA. Mass size, blood loss, and LOH in patients with pheochromocytoma were significantly longer than those in patients with other functional adrenal masses. Thus, mass functionality did not increase the complications.
METHODS: The study included 298 patients, 154 of whom were diagnosed with nonfunctional masses. In the functional group, 33, 62, and 59 patients had Conn syndrome, Cushing\'s syndrome, and pheochromocytoma, respectively. The variables were analyzed between the functional and nonfunctional groups and then compared among functional masses through subgroup analysis.
RESULTS: The incidence of diabetes mellitus, hypertension, and obesity, blood loss, and length of hospital stay (LOH) were significantly higher in the functional group than in the nonfunctional group. In the subgroup analysis, patients with pheochromocytoma had significantly lower body mass index but significantly higher mass size, blood loss, and LOH than the other two groups. A positive correlation was found between mass size and blood loss in patients with pheochromocytoma (p ≤ 0.001, r = 0.761). However, no significant difference in complications was found among the groups.
CONCLUSIONS: In this study, patients with functional adrenal masses had higher comorbidity rates and American Society of Anesthesiologists scores. Moreover, blood loss and LOH were longer on patients with functional adrenal masses who underwent LA. Mass size, blood loss, and LOH in patients with pheochromocytoma were significantly longer than those in patients with other functional adrenal masses. Thus, mass functionality did not increase the complications.
摘要：
目的：本研究旨在确定肾上腺肿块功能和肾上腺肿块合成的不同激素亚型对腹腔镜肾上腺切除术（LA）结局的影响。
方法：该研究包括298名患者，其中154人被诊断为无功能肿块。在功能组中，33、62和59例患者患有康恩综合征，库欣综合征,嗜铬细胞瘤,分别。在功能组和非功能组之间分析变量，然后通过亚组分析在功能质量之间进行比较。
结果：糖尿病的发病率，高血压,肥胖，失血,功能组的住院时间（LOH）明显高于非功能组。在亚组分析中，嗜铬细胞瘤患者的体重指数明显较低，但肿块大小明显较高，失血,和LOH比其他两组。嗜铬细胞瘤患者的肿块大小与失血量呈正相关（p≤0.001，r=0.761）。然而,各组间并发症无显著差异。
结论：在这项研究中，功能性肾上腺肿块患者的合并症发生率和美国麻醉医师协会评分较高.此外，有功能性肾上腺肿块且接受LA的患者失血和LOH时间更长.质量大小,失血,嗜铬细胞瘤患者的LOH明显长于其他功能性肾上腺肿块患者。因此，肿块功能并未增加并发症.
方法：该研究包括298名患者，其中154人被诊断为无功能肿块。在功能组中，33、62和59例患者患有康恩综合征，库欣综合征,嗜铬细胞瘤,分别。在功能组和非功能组之间分析变量，然后通过亚组分析在功能质量之间进行比较。
结果：糖尿病的发病率，高血压,肥胖，失血,功能组的住院时间（LOH）明显高于非功能组。在亚组分析中，嗜铬细胞瘤患者的体重指数明显较低，但肿块大小明显较高，失血,和LOH比其他两组。嗜铬细胞瘤患者的肿块大小与失血量呈正相关（p≤0.001，r=0.761）。然而,各组间并发症无显著差异。
结论：在这项研究中，功能性肾上腺肿块患者的合并症发生率和美国麻醉医师协会评分较高.此外，有功能性肾上腺肿块且接受LA的患者失血和LOH时间更长.质量大小,失血,嗜铬细胞瘤患者的LOH明显长于其他功能性肾上腺肿块患者。因此，肿块功能并未增加并发症.
