PDF(Pubmed)
Abstract：
Immune-related adverse events (irAEs) are complications of the use of immune checkpoint inhibitors (ICIs). ICI-associated gastritis is one of the main irAEs. The gastric microbiota is often related to the occurrence and development of many gastric diseases. Gastric microbiota adjustment may be used to treat gastric disorders in the future. Faecal microbiota transplantation can alter the gut microbiota of patients and has been used for treating ICI-associated colitis. Therefore, we propose gastric microbiota transplantation as a supplementary treatment for patients with ICI-associated gastritis who do not respond well to conventional therapy.
摘要：
免疫相关不良事件(irAE)是使用免疫检查点抑制剂(ICIs)的并发症。ICI相关性胃炎是主要的IRAE之一。胃微生物群往往与许多胃病的发生、发展有关。未来胃微生物群调整可用于治疗胃病。粪便微生物群移植可以改变患者的肠道微生物群，并已用于治疗ICI相关的结肠炎。因此,对于常规治疗效果不佳的ICI相关性胃炎患者,我们建议将胃微生物移植作为辅助治疗.
