Abstract:
High-resolution imaging methods of the iridocorneal angle (ICA) will lead to enhanced understanding of aqueous humor outflow mechanisms and a characterization of the trabecular meshwork (TM) morphology at the cellular level will help to better understand glaucoma mechanics (e.g., cellular level biomechanics of the particulate glaucomas). This information will translate into immense clinical value, leading to more informed and customized treatment selection, and improved monitoring of procedural interventions that lower intraocular pressure (IOP). Given ICA anatomy, imaging modalities that yield intrinsic optical sectioning or 3D imaging capability will be useful to aid in the visualization of TM layers. This minireview examines advancements in imaging the ICA in high-resolution.
摘要:
虹膜角膜角(ICA)的高分辨率成像方法将导致对房水流出机制的增强理解,并且在细胞水平上表征小梁网(TM)形态将有助于更好地了解青光眼力学(例如,颗粒青光眼的细胞水平生物力学)。这些信息将转化为巨大的临床价值,导致更明智和定制的治疗选择,并改进了对降低眼内压(IOP)的手术干预措施的监测。鉴于ICA解剖学,产生固有光学切片或3D成像能力的成像模态将有助于TM层的可视化。这篇小型评论探讨了以高分辨率成像ICA的进展。