通过 EM 连接组学对视网膜回路的新见解：我们学到了什么，还有什么需要学习。New insights into retinal circuits through EM connectomics: what we have learnt and what remains to be learned.-医云文献数字医云科研云海量医学决策数据服务

Abstract：

The retinal neural circuit is intricately wired for efficient processing of visual signals. This is well-supported by the specialized connections between retinal neurons at both the functional and ultrastructural levels. Through 3D electron microscopic (EM) reconstructions of retinal neurons and circuits we have learnt much about the specificities of connections within the retinal layers including new insights into how retinal neurons establish connections and perform sophisticated visual computations. This mini-review will summarize the retinal circuitry and provide details about the novel insights EM connectomics has brought into our understanding of the retinal circuitry. We will also discuss unresolved questions about the retinal circuitry that can be addressed by EM connectomics in the future.

摘要：

视网膜神经回路是复杂的连线，用于有效处理视觉信号。视网膜神经元在功能和超微结构水平上的专门连接得到了很好的支持。通过视网膜神经元和电路的3D电子显微镜（EM）重建，我们已经了解了视网膜层中连接的特异性，包括对视网膜神经元如何建立连接和执行复杂的视觉计算的新见解。这篇小型评论将总结视网膜电路，并提供有关EM连接组学为我们对视网膜电路的理解带来的新颖见解的详细信息。我们还将讨论有关视网膜电路的未解决的问题，这些问题将来可以通过EM连接组学解决。