Abstract:
Background: Malignant melanoma (MM) is one of the most prevalent and deadliest forms of skin cancer, resulting from the malignant transformation of melanocytes. It accounts for approximately 1.7% of global cancer diagnoses and is the fifth most common cancer in the US. MM can metastasize to almost any part of the body, with early detection significantly improving prognosis. Case presentation: We report the case of an 81-year-old female with a history of malignant melanoma (primary lesion on the left calf) and various comorbidities. She presented with severe anemia of unknown origin. A CT scan was performed due to her medical history, revealing a circumferential, asymmetrical parietal thickening at the level of a hypogastric ileal loop. The lesion suggested a tumoral substrate. Subsequent colonoscopy showed no metastatic lesions, but surgical intervention confirmed a malignant melanoma ileal metastasis. The patient underwent laparoscopic segmental resection with favorable post-surgery outcomes. Histopathological examination of the resected tissue confirmed the diagnosis of small intestine secondary lesions from the malignant melanoma. Conclusion: This case underscores the necessity of considering metastatic melanoma in patients with a history of MM and vague gastrointestinal symptoms. Early and accurate diagnosis through advanced imaging and endoscopic techniques can significantly improve patient outcomes.
摘要:
背景:恶性黑色素瘤(MM)是最常见和最致命的皮肤癌之一。黑素细胞的恶性转化。它约占全球癌症诊断的1.7%,是美国第五大最常见的癌症。MM几乎可以转移到身体的任何部位,早期检测显著改善预后。病例介绍:我们报告了一名81岁的女性,有恶性黑色素瘤(左小腿原发性病变)和各种合并症的病史。她表现为不明原因的严重贫血。根据她的病史做了CT扫描,揭示了一个圆周,腹下回肠环水平的不对称顶叶增厚。病变提示肿瘤底物。随后的结肠镜检查显示没有转移性病变,但手术证实恶性黑色素瘤回肠转移。患者接受了腹腔镜节段切除术,术后效果良好。切除组织的组织病理学检查证实了恶性黑色素瘤小肠继发性病变的诊断。结论:该病例强调了有MM病史和胃肠道症状模糊的患者考虑转移性黑色素瘤的必要性。通过先进的成像和内窥镜技术进行早期准确的诊断可以显着改善患者的预后。