METHODS: Employment status, monthly income, days absent from work, and presenteeism were collected at diagnosis and 1 year later to estimate the annual costs of unemployment, absenteeism, and presenteeism using human capital approach. Non-parametric bootstrapping was performed to account for the uncertainty of the estimated costs.
RESULTS: Compared to patients with OA (n = 64), patients with IA (n = 102, including 48 rheumatoid arthritis, 19 spondyloarthritis, 23 psoriatic arthritis, and 12 seronegative IA patients) were younger (mean age: 52.3 vs. 59.5 years) with a greater proportion receiving treatment (99.0% vs. 67.2%) and a greater decrease in presenteeism score (median: 15% vs 10%) 1 year after diagnosis. Annual costs of absenteeism and presenteeism were lower in patients with IA than those with OA both in the year before (USD566 vs. USD733 and USD8,472 vs. USD10,684, respectively) and after diagnosis (USD636 vs. USD1,035 and USD6,866 vs. USD9,362, respectively).
CONCLUSIONS: Both IA and OA impose substantial cost of lost productivity in the year before and after diagnosis. The greater improvement in productivity seen in patients with IA suggests that treatment for IA improves work productivity.
方法:就业状况,月收入,天不上班,并在诊断时和一年后收集出勤率,以估计每年的失业成本,旷工,和使用人力资本方法的出勤主义。执行非参数引导以考虑估计成本的不确定性。
结果:与OA患者(n=64)相比,IA患者(n=102,包括48例类风湿关节炎,19脊柱关节炎,23银屑病关节炎,和12名血清阴性IA患者)更年轻(平均年龄:52.3vs.59.5年),接受治疗的比例更高(99.0%vs.67.2%),并且在诊断后1年出现的评分下降更大(中位数:15%vs10%)。前一年,IA患者的缺勤和出勤费用均低于OA患者(USD566vs.USD733和USD8,472vs.分别为10,684美元)和诊断后(636美元与USD1,035和USD6,866vs.分别为9,362美元)。
结论:IA和OA都会在诊断前后的一年中造成巨大的生产力损失。IA患者的生产率有了更大的提高,这表明IA的治疗可以提高工作效率。