Abstract：
OBJECTIVE: Electrocardiographic left ventricular hypertrophy (ECG LVH) holds significant clinical importance in cardiovascular disease. Pathological processes that lead to left ventricular hypertrophy (LVH) also induce remodeling and impair left atrial (LA) function. Atrial function can be assessed using speckle-tracking echocardiography. This study investigates the potential impact of ECG LVH on LA strain.
METHODS: A total of 62 individuals diagnosed with LVH, based on the echocardiographic left ventricular mass index, were included. ECG LVH was assessed using established protocols: the Sokolow-Lyon voltage criteria (SV1 + RV5/RV6 > 35 mm), Cornell voltage criteria (RaVL + SV3 > 28 mm for men and > 20 mm for women), and the Cornell product criteria [(SV3 + RaVL + (for women 8 mm)] x QRS duration > 2440 mm x ms). Participants were categorized into two groups based on the presence or absence of ECG LVH. The relationship between LA strain measures and ECG characteristics was explored.
RESULTS: The study population had a median age of 58.3 ± 10.1 years, with 40.3% being female, 91.9% hypertensive, and 35.5% diabetic. Nineteen patients (30.6%) were identified with ECG LVH based on Sokolow-Lyon voltage, Cornell voltage, or Cornell product criteria. These patients exhibited significantly reduced LA reservoir, conduit, and contraction strains (P < 0.001). Statistically significant correlations were observed between all three phases of LA strain measures and Sokolow-Lyon voltage (reservoir r = -0.389, P < 0.01; conduit r = -0.273, P < 0.05; contraction r = -0.359, P < 0.01), Cornell voltage (reservoir r = -0.49, P < 0.001; conduit r = -0.432, P < 0.001; contraction r = -0.339, P < 0.01), and Cornell product (reservoir r = -0.471, P < 0.001; conduit r = -0.387, P < 0.01; contraction r = -0.362, P < 0.01).
CONCLUSIONS: ECG LVH is associated with impaired LA strain, validating its use as an effective tool for predicting LA dysfunction.
METHODS: A total of 62 individuals diagnosed with LVH, based on the echocardiographic left ventricular mass index, were included. ECG LVH was assessed using established protocols: the Sokolow-Lyon voltage criteria (SV1 + RV5/RV6 > 35 mm), Cornell voltage criteria (RaVL + SV3 > 28 mm for men and > 20 mm for women), and the Cornell product criteria [(SV3 + RaVL + (for women 8 mm)] x QRS duration > 2440 mm x ms). Participants were categorized into two groups based on the presence or absence of ECG LVH. The relationship between LA strain measures and ECG characteristics was explored.
RESULTS: The study population had a median age of 58.3 ± 10.1 years, with 40.3% being female, 91.9% hypertensive, and 35.5% diabetic. Nineteen patients (30.6%) were identified with ECG LVH based on Sokolow-Lyon voltage, Cornell voltage, or Cornell product criteria. These patients exhibited significantly reduced LA reservoir, conduit, and contraction strains (P < 0.001). Statistically significant correlations were observed between all three phases of LA strain measures and Sokolow-Lyon voltage (reservoir r = -0.389, P < 0.01; conduit r = -0.273, P < 0.05; contraction r = -0.359, P < 0.01), Cornell voltage (reservoir r = -0.49, P < 0.001; conduit r = -0.432, P < 0.001; contraction r = -0.339, P < 0.01), and Cornell product (reservoir r = -0.471, P < 0.001; conduit r = -0.387, P < 0.01; contraction r = -0.362, P < 0.01).
CONCLUSIONS: ECG LVH is associated with impaired LA strain, validating its use as an effective tool for predicting LA dysfunction.
摘要：
目的：心电图左心室肥厚（ECGLVH）在心血管疾病中具有重要的临床意义。导致左心室肥大（LVH）的病理过程也会诱导重塑并损害左心房（LA）功能。可以使用斑点追踪超声心动图评估心房功能。这项研究调查了ECGLVH对LA应变的潜在影响。
方法：共62例诊断为LVH，基于超声心动图左心室质量指数,包括在内。使用已建立的方案评估ECGLVH：Sokolow-Lyon电压标准（SV1+RV5/RV6>35mm），康奈尔电压标准（男性RaVL+SV3>28mm，女性>20mm），和Cornell产品标准[(SV3+RaVL+(女性8mm)]xQRS持续时间>2440mmxms)。根据是否存在ECGLVH将参与者分为两组。探索LA应变测量值与心电图特征之间的关系。
结果：研究人群的中位年龄为58.3±10.1岁，40.3%是女性，91.9%高血压，和35.5%的糖尿病患者。根据Sokolow-Lyon电压确定了19例患者（30.6%）的心电图LVH，康奈尔电压,或康奈尔产品标准。这些患者表现出明显减少的LA储库，导管,和收缩应变（P<0.001）。在所有三个阶段的LA应变测量值与Sokolow-Lyon电压之间观察到统计学上的显着相关性（储层r=-0.389，P<0.01；导管r=-0.273，P<0.05；收缩r=-0.359，P<0.01），康奈尔电压（储层r=-0.49，P<0.001；导管r=-0.432，P<0.001；收缩r=-0.339，P<0.01），和康奈尔产品（储层r=-0.471，P<0.001；导管r=-0.387，P<0.01；收缩r=-0.362，P<0.01）。
结论：心电图LVH与LA劳损相关，验证其作为预测LA功能障碍的有效工具的用途。
方法：共62例诊断为LVH，基于超声心动图左心室质量指数,包括在内。使用已建立的方案评估ECGLVH：Sokolow-Lyon电压标准（SV1+RV5/RV6>35mm），康奈尔电压标准（男性RaVL+SV3>28mm，女性>20mm），和Cornell产品标准[(SV3+RaVL+(女性8mm)]xQRS持续时间>2440mmxms)。根据是否存在ECGLVH将参与者分为两组。探索LA应变测量值与心电图特征之间的关系。
结果：研究人群的中位年龄为58.3±10.1岁，40.3%是女性，91.9%高血压，和35.5%的糖尿病患者。根据Sokolow-Lyon电压确定了19例患者（30.6%）的心电图LVH，康奈尔电压,或康奈尔产品标准。这些患者表现出明显减少的LA储库，导管,和收缩应变（P<0.001）。在所有三个阶段的LA应变测量值与Sokolow-Lyon电压之间观察到统计学上的显着相关性（储层r=-0.389，P<0.01；导管r=-0.273，P<0.05；收缩r=-0.359，P<0.01），康奈尔电压（储层r=-0.49，P<0.001；导管r=-0.432，P<0.001；收缩r=-0.339，P<0.01），和康奈尔产品（储层r=-0.471，P<0.001；导管r=-0.387，P<0.01；收缩r=-0.362，P<0.01）。
结论：心电图LVH与LA劳损相关，验证其作为预测LA功能障碍的有效工具的用途。
