PDF(Pubmed)
Abstract：
BACKGROUND: Pilomatricoma (PM) is a cutaneous benign neoplasm derived from the hair matrix. It clinically presents as a solitary and firm nodule overlying normal epidermis and is usually not easy to be noticed at early stage. Nevertheless, when special bullous lesion occurs in a short time or even ulcerates, preoperative diagnosis by a dermatologist is often challenging especially when the pediatric patients refuse biopsy.
METHODS: We present six bullous PM cases and particularly conduct correlation analysis on the dermotoscopy and histopathology detection data. The basic information, medical history, symptoms and lesion morphology results of the patients were also provided. We found that the incidence of bullous PM was higher in females than in males, and most patients were adolescents and the predilection location seem to be consistent in the vaccine injection site. The dermatoscopic features of bullous PM reported were luminous yellow structure below, with gray-blue homogeneous areas and branched capillary. The histological features were consistent with PM, and evident epidermis bullae were above the tumor with extraordinary dilation of lymphangion in the upper dermis. The patients described in this study were Chinese patients in Han population included 4 females and 2 males, coincidentally, they are almost teen-age, respectively are 5,11,17,19,21,22 year-old.
CONCLUSIONS: This study reported and analyzed the dermotoscopy and clinical characteristics of bullous PM, dermotoscopy may guide as a rapid and reliable technique in bullous PM diagnosis.
METHODS: We present six bullous PM cases and particularly conduct correlation analysis on the dermotoscopy and histopathology detection data. The basic information, medical history, symptoms and lesion morphology results of the patients were also provided. We found that the incidence of bullous PM was higher in females than in males, and most patients were adolescents and the predilection location seem to be consistent in the vaccine injection site. The dermatoscopic features of bullous PM reported were luminous yellow structure below, with gray-blue homogeneous areas and branched capillary. The histological features were consistent with PM, and evident epidermis bullae were above the tumor with extraordinary dilation of lymphangion in the upper dermis. The patients described in this study were Chinese patients in Han population included 4 females and 2 males, coincidentally, they are almost teen-age, respectively are 5,11,17,19,21,22 year-old.
CONCLUSIONS: This study reported and analyzed the dermotoscopy and clinical characteristics of bullous PM, dermotoscopy may guide as a rapid and reliable technique in bullous PM diagnosis.
摘要：
背景：Pilomatricoma（PM）是一种源自毛发基质的皮肤良性肿瘤。它在临床上表现为覆盖正常表皮的孤立而坚固的结节，通常在早期不容易被注意到。然而，当特殊的大疱性病变在短时间内发生甚至溃疡时，皮肤科医生的术前诊断通常具有挑战性，尤其是当儿科患者拒绝活检时。
方法：我们介绍了6例大疱性PM病例，特别是对皮肤镜检查和组织病理学检测数据进行了相关性分析。基本信息,病史,还提供了患者的症状和病变形态结果。我们发现女性大疱性PM的发病率高于男性，大多数患者是青少年，好发部位似乎与疫苗注射部位一致。报告的大疱性PM的皮肤镜特征是下面的发光黄色结构，具有灰蓝色均匀区域和分支毛细管。组织学特征与PM一致，肿瘤上方有明显的表皮大疱，真皮上部淋巴结异常扩张。本研究中描述的患者是汉族人群中的中国患者，包括4名女性和2名男性，巧合的是，他们几乎是青少年，分别为5,11,17,19,21,22岁。
结论：本研究报告并分析了大疱性PM的皮肤镜检查和临床特征，皮肤镜检查可以作为一种快速可靠的大疱性PM诊断技术。
方法：我们介绍了6例大疱性PM病例，特别是对皮肤镜检查和组织病理学检测数据进行了相关性分析。基本信息,病史,还提供了患者的症状和病变形态结果。我们发现女性大疱性PM的发病率高于男性，大多数患者是青少年，好发部位似乎与疫苗注射部位一致。报告的大疱性PM的皮肤镜特征是下面的发光黄色结构，具有灰蓝色均匀区域和分支毛细管。组织学特征与PM一致，肿瘤上方有明显的表皮大疱，真皮上部淋巴结异常扩张。本研究中描述的患者是汉族人群中的中国患者，包括4名女性和2名男性，巧合的是，他们几乎是青少年，分别为5,11,17,19,21,22岁。
结论：本研究报告并分析了大疱性PM的皮肤镜检查和临床特征，皮肤镜检查可以作为一种快速可靠的大疱性PM诊断技术。
