Abstract：
The Advanced Oxidative Processes have demonstrated potential for application in the degradation of organic pollutants, such as Paraquat (PQ) from water and wastewater, due to their low price, high efficiency, and non-toxic properties. In this study, we investigated whether the photodegradation of PQ with TiO2 nanotubes reduced its toxicity in Drosophila melanogaster. However, dietary ingestion of degradation products PQ for larvae resulted in a low axial ratio (pupal volume). In the adults, products of photodegradation of PQ exposure markedly diminished climbing ability in a time-dependent manner after 10 days of feeding. In addition, exposure of D. melanogaster to photodegradation of PQ reduced acetylcholinesterase and citrate synthase activities but improved oxidative stress, as evidenced by oxide nitric, protein carbonyl, and lactate production. These results suggest that the photodegradation of PQ with TiO2 nanotubes produced PQ fragments with higher toxicity than PQ, while the precise mechanism of its action needs further investigation.
摘要：
先进的氧化过程已经证明了在有机污染物的降解应用的潜力，如水和废水中的百草枯(PQ)，由于价格低廉,效率高,和无毒特性。在这项研究中,我们研究了TiO2纳米管对PQ的光降解是否降低了其对果蝇的毒性。然而,幼虫的降解产物PQ的饮食摄入导致轴比（p体积）低。在成年人中，喂食10天后，PQ暴露的光降解产物以时间依赖性方式显着降低了攀爬能力。此外,D.melanogaster暴露于PQ的光降解降低了乙酰胆碱酯酶和柠檬酸合酶的活性，但改善了氧化应激，正如一氧化氮所证明的那样，蛋白质羰基，和乳酸生产。这些结果表明，PQ与TiO2纳米管的光降解产生的PQ片段具有比PQ更高的毒性，而其作用的确切机制需要进一步研究。
