Abstract：
Adipocytic tumors are mesenchymal tumors that are commonly reported in psittacine birds; however, large-scale studies evaluating their prevalence and associated risk factors are lacking. A retrospective study of adipocytic tumors in psittacine birds was performed by reviewing pathology submissions from the University of California, Davis-Drury Reavill Pathology Database, containing 26 013 submissions from psittacine birds (1998-2018). Age, sex, genus, anatomic distribution, and pathological diagnosis were collected for each case when available. The prevalence, risk factors, and association with other lipid-accumulation disorders were reported. A total of 450 cases of lipoma, 129 cases of myelolipoma, 35 cases of hemangiolipoma, 31 cases of liposarcoma, and 451 cases of xanthoma were identified. The prevalence of adipocytic tumors and xanthomas on necropsy was 1.3% (158/11 737, 95% confidence interval [CI]: 1.1-1.6). Adipocytic tumors were identified in 27 genera. Amazona (odds ratio [OR] = 1.93, 95% CI: 1.24-2.99, p = 0.004), Myiopsitta (OR = 2.3, 95% CI: 1.0-5.2, p = 0.041), Melopsittacus (OR = 3.4, 95% CI: 2.1-5.5, p < 0.001), and Agapornis (OR = 3.5, 95% CI: 2.0-6.1, p < 0.001) had significantly higher odds of developing adipocytic tumors compared with other genera, whereas Ara had significantly lower odds (OR = 0.5, 95% CI: 0.3-0.9, p = 0.030). Age was also a significant risk factor for many types of adipocytic tumors. There was no significant association between general adipocytic tumor formation and atherosclerosis or hepatic lipidosis. Xanthomas were associated with atherosclerosis (OR = 1.88, 95% CI: 1.01-3.51, p = 0.048), but not hepatic lipidosis (p = 0.503). On necropsy, the trunk and air sacs were the most common sites of xanthoma formation, whereas the trunk and liver were the most common sites of lipoma and myelolipoma formation, respectively.
摘要：
脂肪细胞肿瘤是间充质肿瘤，通常在psittacine鸟类中报道;然而，缺乏评估其患病率和相关危险因素的大规模研究.通过回顾加利福尼亚大学的病理学报告，对鹦鹉汀鸟类的脂肪细胞肿瘤进行了回顾性研究。Davis-DruryReavill病理学数据库，包含26013份来自鹦鹉鸟（1998-2018年）。年龄,性别,属,解剖分布,并收集每个病例的病理诊断。患病率,危险因素，并报告了与其他脂质蓄积障碍的相关性。脂肪瘤共450例,129例髓脂肪瘤，血管脂肪瘤35例,脂肪肉瘤31例,共发现黄瘤451例。尸检时脂肪细胞瘤和黄色瘤的患病率为1.3％（158/11737，95％置信区间[CI]：1.1-1.6）。在27个属中鉴定出脂肪细胞肿瘤。亚马逊(赔率比[OR]=1.93，95%CI：1.24-2.99，p=0.004)，Myiopsitta（OR=2.3，95%CI：1.0-5.2，p=0.041），Meopsittacus（OR=3.4，95％CI：2.1-5.5，p<0.001），与其他属相比，Agapornis（OR=3.5，95％CI：2.0-6.1，p<0.001）发生脂肪细胞肿瘤的几率明显更高，而Ara的几率显著较低（OR=0.5，95%CI：0.3-0.9，p=0.030）。年龄也是许多类型的脂肪细胞肿瘤的重要危险因素。一般脂肪细胞瘤的形成与动脉粥样硬化或肝脏脂肪沉着之间没有显着关联。黄色瘤与动脉粥样硬化相关(OR=1.88,95%CI:1.01-3.51,p=0.048),但不是肝脂沉着（p=0.503）。尸检时,树干和气囊是黄色瘤形成的最常见部位，而躯干和肝脏是脂肪瘤和骨髓脂肪瘤形成的最常见部位，分别。
