METHODS: A case-control study was done on 100 patients with type 2 diabetes and 100 healthy controls attending Alwafa Center for Diabetes and Endocrinology and four family medicine health centers in Mosul for the period 1st of January 2024-30th of March 2024. Data collection was done by a direct interview with participants. Hematological indices were tested by using an automatic hematology analyzer.
RESULTS: Statistically significant differences in Hb were found between diabetic patients and controls (P = 0.007). The total WBC count, neutrophils, and lymphocytes were significantly higher in diabetic patients compared to controls (P = 0.001 for all). Moreover, platelet indices (platelets count and PDW) showed a significant difference between diabetic patients and controls (P = 0.004 and 0.000) respectively. In addition, total WBC count, neutrophil count, and lymphocytes show a statistically significant positive correlation with FBS (P = 0.026, 0.050, and 0.019) respectively.
CONCLUSIONS: This study revealed statistically significant differences in various hematological parameters between patients with type 2 diabetes and healthy controls. Regular testing of hematological indices helps in early detection and proper management of diabetic complications.
方法:在2024年1月1日至2024年3月30日期间,对100名2型糖尿病患者和100名健康对照者进行了病例对照研究。数据收集是通过与参与者的直接访谈完成的。使用自动血液学分析仪测试血液学指标。
结果:发现糖尿病患者和对照组之间Hb的统计学差异显着(P=0.007)。白细胞总数,中性粒细胞,与对照组相比,糖尿病患者的淋巴细胞明显更高(全部P=0.001)。此外,血小板指数(血小板计数和PDW)在糖尿病患者和对照组之间分别具有显着差异(P=0.004和0.000)。此外,白细胞总数,中性粒细胞计数,和淋巴细胞分别与FBS呈统计学显著正相关(P=0.026、0.050和0.019)。
结论:这项研究揭示了2型糖尿病患者与健康对照组之间各种血液学参数的统计学差异。定期检测血液学指标有助于糖尿病并发症的早期发现和适当管理。