Abstract：
UNASSIGNED: Low back pain (LBP) is a debilitating phenomenon that significantly impacts quality-of-life (QoL). The PainDETECT questionnaire (PD-Q) is a screening tool aimed at distinguishing nociceptive pain (NoP) and neuropathic pain (NeP) classifications. Associations between these classifications and patient-reported outcome measures (PROMs) and sociodemographic parameters are yet to be established.
UNASSIGNED: The study aimed to determine the relationship between NeP as assessed by the PD-Q and pain, disability, QoL, and sociodemographic factors.
UNASSIGNED: A retrospective analysis of an ongoing prospectively collected database was conducted involving 512 patients aged >18 years who presented to a tertiary spine clinic for LBP having completed the PainDETECT questionnaire, Oswestry Disability Index (ODI), EuroQol Five-Dimensional (EQ-5D) questionnaire, or answered questions regarding sociodemographic status.
UNASSIGNED: The NeP group had a higher mean numerical rating scale (NRS) score (7.96±1.54 vs. 5.76±2.27, p <.001) and lower age (55±15.6 vs. 59±17.8, p <.05) compared to the NoP group. When confounded for NRS, analysis of covariance demonstrated an 89.5% higher total ODI score (p <.001) and 50.5% lower EQ-5D utility score (p <.001) in the NeP compared to NoP group. Smokers and individuals with a no partner marital status were 2.373 (OR = 2.373, 95% CI = 1.319-4.266, p <.01) and 2.384 times (OR = 2.384, 95% CI = 1.390-4.092, p <.01) more likely to have NeP compared to NoP, respectively. Patients with NeP were also of lower income class compared to patients with NoP (Z = -2.45, p <.05).
UNASSIGNED: NeP was associated with higher levels of disability and lower QoL. Smokers, individuals with a no partner marital status, and individuals with a lower income class were more likely to suffer NeP rather than NoP. These findings have illuminated a crucial notion: in patients with elevated NRS, the detrimental impact of NeP on patient wellbeing underscores the fundamental need to represent pain on a nociceptive-neuropathic continuum, permitting more accurate differentiation of pain components.
UNASSIGNED: The study aimed to determine the relationship between NeP as assessed by the PD-Q and pain, disability, QoL, and sociodemographic factors.
UNASSIGNED: A retrospective analysis of an ongoing prospectively collected database was conducted involving 512 patients aged >18 years who presented to a tertiary spine clinic for LBP having completed the PainDETECT questionnaire, Oswestry Disability Index (ODI), EuroQol Five-Dimensional (EQ-5D) questionnaire, or answered questions regarding sociodemographic status.
UNASSIGNED: The NeP group had a higher mean numerical rating scale (NRS) score (7.96±1.54 vs. 5.76±2.27, p <.001) and lower age (55±15.6 vs. 59±17.8, p <.05) compared to the NoP group. When confounded for NRS, analysis of covariance demonstrated an 89.5% higher total ODI score (p <.001) and 50.5% lower EQ-5D utility score (p <.001) in the NeP compared to NoP group. Smokers and individuals with a no partner marital status were 2.373 (OR = 2.373, 95% CI = 1.319-4.266, p <.01) and 2.384 times (OR = 2.384, 95% CI = 1.390-4.092, p <.01) more likely to have NeP compared to NoP, respectively. Patients with NeP were also of lower income class compared to patients with NoP (Z = -2.45, p <.05).
UNASSIGNED: NeP was associated with higher levels of disability and lower QoL. Smokers, individuals with a no partner marital status, and individuals with a lower income class were more likely to suffer NeP rather than NoP. These findings have illuminated a crucial notion: in patients with elevated NRS, the detrimental impact of NeP on patient wellbeing underscores the fundamental need to represent pain on a nociceptive-neuropathic continuum, permitting more accurate differentiation of pain components.
摘要：
背景：下腰痛（LBP）是一种使人衰弱的现象，显着影响生活质量（QOL）。PainDETECT问卷（PD-Q）是一种筛选工具，旨在区分伤害性疼痛（NoP）和神经性疼痛（NeP）分类。这些分类与患者报告的结果测量（PROM）和社会人口统计学参数之间的关联尚未建立。目的：本研究旨在确定通过PD-Q评估的NeP与疼痛之间的关系，残疾,生活质量和社会人口因素。方法：对正在进行的前瞻性收集的数据库进行了回顾性分析，该数据库涉及512名年龄>18岁的患者，这些患者在完成PainDETECT问卷后出现在三级脊柱诊所接受LBP治疗。Oswestry残疾指数（ODI），EuroQol五维（EQ-5D）问卷或回答有关社会人口状况的问题。结果：NeP组的平均数字评定量表（NRS）得分较高（7.96±1.54vs.5.76±2.27，p<0.001）和较低的年龄（55±15.6vs.59±17.8，p<0.05）与NoP组相比。当被NRS混淆时，协方差分析显示，与NoP组相比，NeP组的ODI总评分高89.5%（p<0.001），EQ-5D效用评分低50.5%（p<0.001）。吸烟者和无伴侣婚姻状况的个体为2.373（OR=2.373，95％C.I.[1.319-4.266]，p<0.01）和2.384倍（OR=2.384，95％C.I.[1.390-4.092]，p<0.01)与NoP相比，更有可能具有NeP，分别。与NoP患者相比，NeP患者的收入也较低（Z=-2.45，p<0.05）。结论：NeP与较高的残疾水平和较低的生活质量有关。吸烟者,没有伴侣婚姻状况的人，低收入阶层的个人更有可能遭受NeP而不是NoP。这些发现阐明了一个至关重要的概念：在NRS升高的患者中，NeP对患者健康的有害影响强调了在伤害性-神经性连续体上表现疼痛的基本需要，允许更准确地区分疼痛成分。
