关键词: axillary lymph node breast cancer hemangioma metastasis

Mesh : Humans Female Breast Neoplasms / pathology Lymphatic Metastasis Hemangioma / pathology Lymph Nodes / pathology Middle Aged

来  源:   DOI:10.32074/1591-951X-911

Abstract:
Secondary neoplastic lesions in lymph nodes are predominantly metastases from solid tumors, whereas primary lymph node hemangiomas are exceptionally uncommon, with only 24 well-documented cases in the literature. Histologically, they are characterized by endothelial cells that may appear flattened or enlarged, with variable vascular density, and the presence of stromal elements. Notably, the concurrent presence of a primary hemangioma and a metastasis from breast cancer - the latter being the most prevalent secondary lesion in axillary lymph nodes - represents an unprecedented observation. The unique case presented herein underscores the exceptional rarity of primary lymph node hemangiomas and demonstrates for the first time their possible coexistence with breast cancer metastasis within the same axillary lymph node. In sharing and discussing this case study, we pay homage to Professor Juan Rosai, whose work in redefining rare and complex diagnoses continues to enlighten our understanding of lymph node vascular lesions.
摘要:
淋巴结的继发性肿瘤病变主要是实体瘤的转移,而原发性淋巴结血管瘤异常罕见,文献中只有24例有据可查的病例。组织学上,它们的特征是内皮细胞可能变平或增大,随着血管密度的变化,和基质元素的存在。值得注意的是,同时出现原发性血管瘤和乳腺癌转移-后者是腋窝淋巴结中最常见的继发性病变-这是前所未有的观察结果.本文介绍的独特病例强调了原发性淋巴结血管瘤的罕见性,并首次证明了它们可能与同一腋窝淋巴结内的乳腺癌转移共存。在分享和讨论这个案例研究时,我们向JuanRosai教授致敬,他们在重新定义罕见和复杂诊断方面的工作继续启发我们对淋巴结血管病变的理解。
公众号