关键词: cognitive map entorhinal cortex hippocampus learning and memory olfaction piriform cortex (PC) virtual reality

Mesh : Animals Odorants Olfactory Pathways / physiology Smell / physiology Humans Olfactory Perception / physiology Space Perception / physiology Brain / physiology

来  源:   DOI:10.3389/fncir.2024.1414452   PDF(Pubmed)

Abstract:
As an evolutionarily ancient sense, olfaction is key to learning where to find food, shelter, mates, and important landmarks in an animal\'s environment. Brain circuitry linking odor and navigation appears to be a well conserved multi-region system among mammals; the anterior olfactory nucleus, piriform cortex, entorhinal cortex, and hippocampus each represent different aspects of olfactory and spatial information. We review recent advances in our understanding of the neural circuits underlying odor-place associations, highlighting key choices of behavioral task design and neural circuit manipulations for investigating learning and memory.
摘要:
作为一种进化上古老的感觉,嗅觉是学习在哪里找到食物的关键,庇护所,mates,以及动物环境中的重要地标。连接气味和导航的大脑回路似乎是哺乳动物中保存良好的多区域系统;前嗅核,梨状皮质,内嗅皮层,和海马分别代表嗅觉和空间信息的不同方面。我们回顾了我们对气味-位置关联的神经回路的理解的最新进展,突出研究学习和记忆的行为任务设计和神经电路操作的关键选择。
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