关键词: COVID-19 altitude dementia glutathione hyperbaric pandemic pre-cursors wellness

来  源:   DOI:10.3389/fneur.2024.1356662   PDF(Pubmed)

Abstract:
A 78-year-old man with dementia experienced waxing and waning of symptoms with changes in altitude as he traveled from his home in the Rocky Mountains to lower elevations and back. To replicate the improvement in his symptoms with travel to lower elevations (higher pressure), the patient was treated with a near-identical repressurization in a hyperbaric chamber using compressed air. With four 1-h treatments at 1.3 Atmospheres Absolute (ATA) and concurrent administration of low-dose oral glutathione amino acid precursors, he recovered speech and showed improvement in activities of daily living. Regional broadcast media had documented his novel recovery. Nosocomial COVID-19 and withdrawal of hyperbaric air therapy led to patient demise 7 months after initiation of treatment. It is theorized that hyperbaric air therapy stimulated mitochondrial biochemical and physical changes, which led to clinical improvement.
摘要:
一名78岁的痴呆症患者从落基山脉的家中前往海拔较低的地方并返回时,随着海拔高度的变化,症状出现了起伏和减弱。通过旅行到较低的海拔(较高的压力)来复制他的症状的改善,患者在高压舱中使用压缩空气进行了几乎相同的再加压治疗。在1.3绝对大气(ATA)下进行四次1小时治疗,并同时服用低剂量口服谷胱甘肽氨基酸前体,他恢复了言语,日常生活活动也有所改善。区域广播媒体记录了他的小说康复。医院COVID-19和高压空气治疗的退出导致患者在开始治疗7个月后死亡。从理论上讲,高压空气治疗会刺激线粒体生化和物理变化,导致临床改善。
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