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Abstract：
BACKGROUND: Red Ear Syndrome is a burning sensation and erythema of the ear, associated with a various number of disorders including migraine, trigeminal neuralgia, autoimmune disorders etc. Theories for RES pathophysiology have developed from current understandings of comorbid conditions. Characterizing the underlying mechanism of RES is crucial for defining effective treatments.
METHODS: Three caucasian patients, ages 15, 47, and 67 years, with migraine, one with erythromelalgia are reported in this manuscript. RES pathophysiology is not fully understood due to its variable clinical presentation and numerous comorbid conditions, making it difficult to identify effective treatments.
CONCLUSIONS: RES seems to be largely treatment-resistant, and most options involve treating the associated disorders and minimizing pain. Further investigation of future cases should lead to a more comprehensive understanding of the fundamental cause of RES and, hopefully, successful treatments.
METHODS: Three caucasian patients, ages 15, 47, and 67 years, with migraine, one with erythromelalgia are reported in this manuscript. RES pathophysiology is not fully understood due to its variable clinical presentation and numerous comorbid conditions, making it difficult to identify effective treatments.
CONCLUSIONS: RES seems to be largely treatment-resistant, and most options involve treating the associated disorders and minimizing pain. Further investigation of future cases should lead to a more comprehensive understanding of the fundamental cause of RES and, hopefully, successful treatments.
摘要：
背景：红耳综合症是耳朵的灼烧感和红斑，与包括偏头痛在内的各种疾病相关，三叉神经痛,自身免疫性疾病等.RES病理生理学的理论已经从当前对合并症的理解中发展起来。表征RES的潜在机制对于定义有效治疗至关重要。
方法：三名白种人患者，年龄15、47和67岁，偏头痛,本手稿报道了一例红斑性疼痛。RES病理生理学由于其可变的临床表现和许多合并症而尚未完全理解。很难确定有效的治疗方法。
结论：RES似乎在很大程度上具有治疗抗性，大多数选择包括治疗相关疾病和减少疼痛。对未来案件的进一步调查应导致对RES的根本原因有更全面的了解，希望,成功的治疗。
方法：三名白种人患者，年龄15、47和67岁，偏头痛,本手稿报道了一例红斑性疼痛。RES病理生理学由于其可变的临床表现和许多合并症而尚未完全理解。很难确定有效的治疗方法。
结论：RES似乎在很大程度上具有治疗抗性，大多数选择包括治疗相关疾病和减少疼痛。对未来案件的进一步调查应导致对RES的根本原因有更全面的了解，希望,成功的治疗。
