Abstract：
OBJECTIVE: Recently, handgrip, knee extensor and respiratory muscle strength were proposed as candidate biomarkers to assess the neuromuscular function of vitality capacity in older persons. This umbrella review aims to provide an overview of the available instruments and their measurement properties to assess these biomarkers.
METHODS: The databases PubMed, Web of Science and Embase were systematically screened for systematic reviews and meta-analyses reporting on handgrip, knee extensor or respiratory muscle strength assessments, resulting in 7,555 articles. The COSMIN checklist was used to appraise psychometric properties and the AMSTAR for assessing methodological quality.
RESULTS: Twenty-seven systematic reviews were included in this study. Some of the identified reviews described the psychometric properties of the assessment tools. We found five assessment tools that can be used to measure neuromuscular function in the context of healthy ageing. Those are the handheld dynamometer for handgrip strength, the dynamometer for knee extensor strength and regarding respiratory muscle strength, the sniff nasal inspiratory pressure, maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP).
CONCLUSIONS: The handheld dynamometer for hand grip strength, the dynamometer for knee extensor strength, sniff nasal inspiratory pressure, MIP and MEP were identified. Therefore, these assessments could be used to identify community-dwelling older adults at risk for a declined neuromuscular function in the context of vitality capacity.
METHODS: The databases PubMed, Web of Science and Embase were systematically screened for systematic reviews and meta-analyses reporting on handgrip, knee extensor or respiratory muscle strength assessments, resulting in 7,555 articles. The COSMIN checklist was used to appraise psychometric properties and the AMSTAR for assessing methodological quality.
RESULTS: Twenty-seven systematic reviews were included in this study. Some of the identified reviews described the psychometric properties of the assessment tools. We found five assessment tools that can be used to measure neuromuscular function in the context of healthy ageing. Those are the handheld dynamometer for handgrip strength, the dynamometer for knee extensor strength and regarding respiratory muscle strength, the sniff nasal inspiratory pressure, maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP).
CONCLUSIONS: The handheld dynamometer for hand grip strength, the dynamometer for knee extensor strength, sniff nasal inspiratory pressure, MIP and MEP were identified. Therefore, these assessments could be used to identify community-dwelling older adults at risk for a declined neuromuscular function in the context of vitality capacity.
摘要：
目标：最近，手柄,膝关节伸肌和呼吸肌力被提议作为评估老年人神经肌肉功能活力的候选生物标志物.这篇综述旨在概述可用的仪器及其测量特性，以评估这些生物标志物。
方法：数据库PubMed，对WebofScience和Embase进行了系统筛选，以进行系统评价和荟萃分析，膝关节伸肌或呼吸肌力量评估，产生7,555篇文章。COSMIN清单用于评估心理测量特性，而AMSTAR用于评估方法学质量。
结果：本研究纳入了27项系统评价。一些已确定的评论描述了评估工具的心理测量特性。我们发现了五种评估工具，可用于在健康衰老的背景下测量神经肌肉功能。那些是手握力量的手持式测力计，膝关节伸肌力量和呼吸肌力量的测力计，嗅鼻吸气压力，最大吸气压力（MIP）和最大呼气压力（MEP）。
结论：手握力量的手持式测力计，膝盖伸肌强度测力计,嗅探鼻腔吸气压力,鉴定了MIP和MEP。因此,这些评估可用于确定社区居住的老年人在活力能力方面有神经肌肉功能下降的风险.
方法：数据库PubMed，对WebofScience和Embase进行了系统筛选，以进行系统评价和荟萃分析，膝关节伸肌或呼吸肌力量评估，产生7,555篇文章。COSMIN清单用于评估心理测量特性，而AMSTAR用于评估方法学质量。
结果：本研究纳入了27项系统评价。一些已确定的评论描述了评估工具的心理测量特性。我们发现了五种评估工具，可用于在健康衰老的背景下测量神经肌肉功能。那些是手握力量的手持式测力计，膝关节伸肌力量和呼吸肌力量的测力计，嗅鼻吸气压力，最大吸气压力（MIP）和最大呼气压力（MEP）。
结论：手握力量的手持式测力计，膝盖伸肌强度测力计,嗅探鼻腔吸气压力,鉴定了MIP和MEP。因此,这些评估可用于确定社区居住的老年人在活力能力方面有神经肌肉功能下降的风险.
