Abstract：
Wound healing is a critical but complex biological process of skin tissue repair and regeneration resulting from various systems working together at the cellular and molecular levels. Quick wound healing and the problems associated with traditional wound repair techniques are being overcome with multifunctional materials. Over time, this research area has drawn significant attention. Metal-organic frameworks (MOFs), owning to their peculiar physicochemical characteristics, are now considered a promising class of well-suited porous materials for wound healing in addition to their other biological applications. This detailed literature review provides an overview of the latest developments in MOFs for wound healing applications. We have discussed the synthesis, essential biomedical properties, wound-healing mechanism, MOF-based dressing materials, and their wound-healing applications. The possible major challenges and limitations of MOFs have been discussed, along with conclusions and future perspectives. This overview of the literature review addresses MOFs-based wound healing from several angles and covers the most current developments in the subject. The readers may discover how the MOFs advanced this discipline by producing more inventive, useful, and successful dressings. It influences the development of future generations of biomaterials for the healing and regeneration of skin wounds.
摘要：
伤口愈合是皮肤组织修复和再生的关键但复杂的生物学过程,其产生于细胞和分子水平上共同工作的各种系统。快速伤口愈合和与传统伤口修复技术相关的问题正在用多功能材料克服。随着时间的推移,这一研究领域引起了极大的关注。金属有机骨架(MOFs)，由于它们独特的物理化学特性，除了其他生物学应用外，现在还被认为是一类有前途的非常适合伤口愈合的多孔材料。这篇详细的文献综述概述了MOFs在伤口愈合应用中的最新进展。我们已经讨论了合成，基本的生物医学特性，伤口愈合机制，基于MOF的敷料材料，以及它们的伤口愈合应用。已经讨论了MOFs可能的主要挑战和局限性，以及结论和未来前景。文献综述的概述从几个角度论述了基于MOFs的伤口愈合,并涵盖了该主题的最新发展。读者可能会发现MOF如何通过产生更多的创造性来推进这一学科，有用的,和成功的敷料。它影响了后代用于皮肤伤口愈合和再生的生物材料的发展。
