PDF(Pubmed)
Abstract：
Taking leftover prescribed antibiotics without consulting a healthcare professional is problematic for the efficacy, safety, and antibiotic stewardship. We conducted a cross-sectional survey of adult patients in English and Spanish between January 2020 and June 2021 in six safety-net primary care clinics and two private emergency departments. We assessed the reasons for stopping prescribed antibiotics early and what was done with the leftover antibiotics. Additionally, we determined 1) prior leftover antibiotic use, 2) intention for future use of leftover antibiotics, and 3) sociodemographic factors. Of 564 survey respondents (median age of 51), 45% (251/564) reported a history of stopping antibiotics early, with 171/409 (42%) from safety net and 80/155 (52%) from the private clinics. The most common reason for stopping prescribed antibiotics early was \"because you felt better\" (194/251, 77%). Among survey participants, prior use of leftover antibiotics was reported by 149/564 (26%) and intention for future use of leftover antibiotics was reported by 284/564 (51%). In addition, higher education was associated with a higher likelihood of prior leftover use. Intention for future use of leftover antibiotics was more likely for those with transportation or language barriers to medical care and less likely for respondents with private insurance. Stopping prescribed antibiotics early was mostly ascribed to feeling better, and saving remaining antibiotics for future use was commonly reported. To curb nonprescription antibiotic use, all facets of the leftover antibiotic use continuum, from overprescribing to hoarding, need to be addressed.
摘要：
在没有咨询医疗保健专业人员的情况下服用剩余的处方抗生素对疗效是有问题的，安全,和抗生素管理。我们在2020年1月至2021年6月期间在六个安全网初级保健诊所和两个私人急诊科对英语和西班牙语的成年患者进行了横断面调查。我们评估了早期停止处方抗生素的原因以及剩余抗生素的处理方式。此外,我们确定1)先前剩余的抗生素使用，2)未来使用剩余抗生素的意向，和3)社会人口因素。在564名受访者中（平均年龄为51岁），45％（251/564）报告有早期停用抗生素的历史，其中171/409(42%)来自安全网，80/155(52%)来自私人诊所。早期停止处方抗生素的最常见原因是“因为你感觉好多了”（194/251，77%）。在调查参与者中，149/564(26%)报告以前使用剩余抗生素,284/564报告将来使用剩余抗生素的意向(51%).此外,高等教育与先前剩余使用的可能性更高相关。对于有交通或语言障碍的人来说，未来使用剩余抗生素的可能性更大，而对于有私人保险的受访者则不太可能。早期停止处方抗生素主要是因为感觉好转，和保存剩余的抗生素供将来使用是常见的报道。为了遏制非处方药抗生素的使用，剩余抗生素使用连续体的所有方面，从过量处方到囤积，需要解决。
