PDF(Pubmed)
Abstract：
Primary hyperparathyroidism is characterized by excessive production of parathyroid hormone. As the condition progresses, bone loss primarily occurs due to resorption. A complication of this condition is the formation of fibrotic and cystic changes in the bone, known as brown tumors. These lesions occur in areas of significant bone resorption, where fibrovascular tissue and giant cells replace bone tissue, often accompanied by hemorrhage and hemosiderin deposits. These brown lesions are rare, with an occurrence rate ranging from 1.5% to 4.5%. We present two cases of middle-aged women who had presentations consistent with hyperparathyroidism and presented with complications such as bone pain and numbness. Both underwent parathyroidectomy to manage the cause and recovered after the surgery. These cases emphasize the importance of recognizing primary hyperparathyroidism as a potential cause of abnormal lesions and highlight the diverse presentations associated with this condition.
摘要：
原发性甲状旁腺功能亢进的特征在于甲状旁腺激素的过量产生。随着病情的进展,骨丢失主要是由于再吸收。这种情况的并发症是骨中纤维化和囊性变化的形成，被称为棕色肿瘤。这些病变发生在明显的骨吸收区域，纤维血管组织和巨细胞取代骨组织，常伴有出血和含铁血黄素沉积。这些棕色病变很少见,发生率为1.5%至4.5%。我们介绍了2例中年女性，其表现与甲状旁腺功能亢进一致，并伴有骨痛和麻木等并发症。两者均接受了甲状旁腺切除术以解决原因，并在手术后康复。这些病例强调认识到原发性甲状旁腺功能亢进是异常病变的潜在原因的重要性，并强调了与这种情况相关的各种表现。
