PDF(Pubmed)
Abstract：
Background and objective COVID-19 is a respiratory disease that is highly contagious and is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Symptoms vary from mild to severe, where most of the patients suffer from high fever, severe headaches, dry cough, and exhaustion, while the less common symptoms are diarrhea, loss of taste, sore throat, and loss of smell. Following recovery from COVID-19, some patients displayed a restricted pattern in the function of their lungs. As a result, documenting the effects of COVID-19 after infection is essential since it provides a better understanding of the long-term consequences of COVID-19. Hence, the objective of the present study was to assess pulmonary functions in post-convalescent COVID-19 patients. Methodology A cross-sectional comparative study was conducted among students and staff members of Gulf Medical University for a duration of one year from 2021 to 2022. Through a convenient sampling method, a total of 100 participants were recruited for the present study, in which pulmonary function tests (PFTs) were performed using a spirometer, and O2 levels were measured using a pulse oximeter. Additionally, respiratory rate and pulse rate were monitored. Results The present study highlighted the comparison of PFTs in post-convalescent COVID-19 patients and concluded that smoker and convalescent COVID-19 groups showed non-significant decrease (p>0.05) in forced vital capacity (FVC) prediction, forced expiratory volume in the first second (FEV1) prediction, FEV1/FVC%, forced mid-expiratory flow rate (FEF25-75%) prediction, peak expiratory flow rate (PEFR) prediction, respiratory rate, and pulse rate in comparison to the control group. In comparison to the convalescent COVID-19 group, convalescent COVID-19 smoking patients showed a significant increase in FEV1/FVC% (p=0.04). Additionally, in comparison to the convalescent COVID-19 group, a significant increase in PEFR prediction values was observed with a p-value of 0.045 and in comparison to the smoker group with a p-value of 0.006. Moreover, oxygen saturation (SpO2) levels demonstrated non-significant changes between the groups. Conclusion The study concluded that for FEV1/FVC% and PEFR prediction values among the convalescent COVID-19 smoking patient group, a significant increase was observed in comparison to the convalescent COVID-19 group. This aids healthcare professionals in amending strategies to prevent consequences resulting from post-COVID-19 infection.
摘要：
背景与目的COVID-19是一种高度传染性的呼吸系统疾病，由严重急性呼吸道综合征冠状病毒2（SARS-CoV-2）引起。症状从轻度到重度不等,大多数病人发高烧，严重的头痛,干咳,和疲惫，虽然不太常见的症状是腹泻，失去味道,喉咙痛,和气味的损失。从COVID-19中恢复后，一些患者的肺功能表现出受限的模式。因此,记录感染后COVID-19的影响至关重要，因为它可以更好地了解COVID-19的长期后果。因此，本研究的目的是评估恢复期COVID-19患者的肺功能.方法从2021年到2022年，在海湾医科大学的学生和工作人员中进行了为期一年的横断面比较研究。通过方便的采样方法，本研究共招募了100名参与者，其中使用肺活量计进行肺功能测试（PFTs），和O2水平使用脉搏血氧计测量。此外,监测呼吸率和脉搏率。结果本研究强调了恢复期COVID-19患者中PFTs的比较，并得出结论：吸烟者和恢复期COVID-19组的用力肺活量（FVC）预测没有显着降低（p>0.05）。第一秒用力呼气容积（FEV1）预测，FEV1/FVC%,用力呼气中流速(FEF25-75%)预测，峰值呼气流速（PEFR）预测，呼吸频率,与对照组相比，脉搏率。与康复期COVID-19组相比，恢复期COVID-19吸烟患者的FEV1/FVC%显著升高(p=0.04).此外,与康复期COVID-19组相比，观察到PEFR预测值显著增加,P值为0.045,与吸烟者组相比,P值为0.006.此外，氧饱和度(SpO2)水平显示两组间无显著变化.结论本研究得出的结论是，对于康复期COVID-19吸烟患者组的FEV1/FVC％和PEFR预测值，与恢复期COVID-19组相比，观察到显著增加。这有助于医疗保健专业人员修改策略，以防止COVID-19感染后造成的后果。
