PDF(Pubmed)
Abstract：
Physicians are occasionally confronted with patients presenting psychotic symptoms of organic origin. Therefore, precision in diagnosing the organic basis is pivotal for targeted treatment, addressing the underlying etiology. This case study delineates the nuanced phases of clinical reasoning employed to ascertain a diagnosis of Huntington\'s disease (HD), notably amidst concurrent alcohol dependence. A comprehensive clinical examination and meticulous review of the patient\'s medical history served as linchpins in guiding subsequent investigations toward identifying the etiological underpinnings of the psychotic symptomatology. Furthermore, this case sheds light on the uncommon overlap of HD and Wernicke\'s encephalopathy, compounding diagnostic complexities, especially given the polymorphic nature of HD. The diagnostic intricacies needed precise analysis of the clinical picture and a deep understanding of potential interactions between neurological pathologies and the deleterious effects of alcoholism on the nervous system.
摘要：
医生偶尔会遇到表现出器质性精神病症状的患者。因此,精确诊断有机基础是靶向治疗的关键，解决潜在的病因。本案例研究描述了用于确定亨廷顿病（HD）诊断的临床推理的细微差别阶段。特别是在并发酒精依赖的情况下。全面的临床检查和对患者病史的细致审查是指导后续研究以确定精神病症状的病因基础的关键。此外，此病例揭示了HD和Wernicke脑病的罕见重叠，复杂的诊断复杂性，特别是考虑到HD的多态性质。诊断复杂性需要对临床表现进行精确分析，并深刻理解神经系统病理之间的潜在相互作用以及酒精中毒对神经系统的有害影响。
