PDF(Pubmed)
Abstract：
UNASSIGNED: Thromboembolic disease is a complication of many vasculitides. A common observation is that thromboembolic events coincide with the period of vasculitic disease, but the mechanism by which this occurs remains unclear. Inflammatory thrombosis is now recognized as a symptom of arteritis rheumatic, and vasculitides such as Behçet\'s syndrome (BS), and anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) or giant cell arteritis (GCA). This systematic review aimed to explain recent findings related to etiology, pathophysiology, and treatment methods for BS, AAV, and medium/large-vessel vasculitis.
UNASSIGNED: A comprehensive literature search on English sources from PubMed, Scopus, MEDLINE, Science Direct, ProQuest, AIM, CINAHIL, and ELDIS databases was used to find the relevant articles and reports. The relevant papers (having full text) were obtained until June 2023. Two independent reviewers screened the titles and abstracts of the obtained articles, and a third arbitrator resolved disputes between the reviewers.
UNASSIGNED: It is becoming increasingly clear that certain systemic inflammatory diseases, like vasculitis, are linked to a higher risk of both venous and arterial thrombosis. An increased incidence of thromboembolic disease in AAV has been noted, particularly during times of active disease. Growing evidence supports the use of immunosuppression in the management of venous thrombosis in vasculitis. These patients also have a higher risk of developing ischemic disease.
UNASSIGNED: A comprehensive literature search on English sources from PubMed, Scopus, MEDLINE, Science Direct, ProQuest, AIM, CINAHIL, and ELDIS databases was used to find the relevant articles and reports. The relevant papers (having full text) were obtained until June 2023. Two independent reviewers screened the titles and abstracts of the obtained articles, and a third arbitrator resolved disputes between the reviewers.
UNASSIGNED: It is becoming increasingly clear that certain systemic inflammatory diseases, like vasculitis, are linked to a higher risk of both venous and arterial thrombosis. An increased incidence of thromboembolic disease in AAV has been noted, particularly during times of active disease. Growing evidence supports the use of immunosuppression in the management of venous thrombosis in vasculitis. These patients also have a higher risk of developing ischemic disease.
摘要：
■血栓栓塞性疾病是许多血管炎的并发症。一个常见的观察是血栓栓塞事件与血管疾病的时期一致，但这种情况发生的机制尚不清楚。炎性血栓形成现在被认为是风湿性动脉炎的症状，和血管炎，如Behçet综合征(BS)，和抗中性粒细胞胞浆抗体（ANCA）相关血管炎（AAV）或巨细胞动脉炎（GCA）。本系统综述旨在解释与病因学相关的最新发现，病理生理学,以及BS的治疗方法，AAV,和中/大血管血管炎。
■对PubMed的英文来源进行全面的文献检索，Scopus,MEDLINE,科学直接，ProQuest,AIM,CINAHIL,和ELDIS数据库用于查找相关文章和报告。相关论文(有全文)一直获得到2023年6月。两名独立审稿人筛选了所获得文章的标题和摘要，第三名仲裁员解决了审稿人之间的纠纷。
■越来越清楚的是某些全身性炎症性疾病，比如血管炎,与静脉和动脉血栓形成的高风险有关。已经注意到AAV中血栓栓塞性疾病的发病率增加，特别是在疾病活跃的时候。越来越多的证据支持在血管炎静脉血栓形成的治疗中使用免疫抑制。这些患者发生缺血性疾病的风险也较高。
■对PubMed的英文来源进行全面的文献检索，Scopus,MEDLINE,科学直接，ProQuest,AIM,CINAHIL,和ELDIS数据库用于查找相关文章和报告。相关论文(有全文)一直获得到2023年6月。两名独立审稿人筛选了所获得文章的标题和摘要，第三名仲裁员解决了审稿人之间的纠纷。
■越来越清楚的是某些全身性炎症性疾病，比如血管炎,与静脉和动脉血栓形成的高风险有关。已经注意到AAV中血栓栓塞性疾病的发病率增加，特别是在疾病活跃的时候。越来越多的证据支持在血管炎静脉血栓形成的治疗中使用免疫抑制。这些患者发生缺血性疾病的风险也较高。
