PDF(Pubmed)
Abstract：
Introduction The prevalence of otitis media (OM) is substantial all over the world. Epidemiological data related to the economic burden of OM globally is minimal. The present systematic review was undertaken to estimate the economic burden of this disease in various parts of the world. Objectives An extensive literature search was done using PRISMA guidelines to identify relevant studies that estimated the economic burden of OM in monetary terms. The databases searched were PubMed Central, Ovid, and Embase. The cost estimation was done for one specific year and then compared considering the inflation rate. Data Synthesis The literature search led to the inclusion of 10 studies. The studies evaluated direct and indirect costs in monetary terms. Direct costs (health system and patient perspective) ranged from USD (United States Dollar) 122.64 (Netherlands) to USD 633.6 (USA) per episode of OM. Looking at only the patient perspective, the costs ranged from USD 19.32 (Oman) to USD 80.5 (Saudi Arabia). The total costs (direct and indirect) ranged from USD 232.7 to USD 977 (UK) per episode of OM. The economic burden per year was highest in the USA (USD 5 billion). The incidence of OM episodes was found more in children < 5 years old. Introduction of pneumococcal conjugate vaccines decreased the incidence in children and now the prevalence in adults is of concern. Conclusion The economic burden of OM is relatively high globally and addressing this public health burden is important. Approaches for the prevention, diagnosis, and treatment should be undertaken by the health system to alleviate this disease burden.
摘要：
引言中耳炎(OM)的患病率在全世界是相当大的。与全球OM经济负担相关的流行病学数据很少。进行了本系统综述，以估计该疾病在世界各地的经济负担。目标使用PRISMA指南进行了广泛的文献检索，以确定以货币形式估计OM经济负担的相关研究。搜索的数据库是PubMedCentral，奥维德,和Embase。对一个特定年份进行成本估算，然后考虑通货膨胀率进行比较。数据综合文献检索导致纳入10项研究。这些研究以货币形式评估了直接和间接成本。每集OM的直接费用（卫生系统和患者观点）从122.64美元（美元）（荷兰）到633.6美元（美国）不等。只从病人的角度来看，费用从19.32美元(阿曼)到80.5美元(沙特阿拉伯)不等。每集OM的总成本（直接和间接）从232.7美元到977美元（英国）不等。美国每年的经济负担最高（50亿美元）。在5岁以下的儿童中，OM发作的发生率更高。肺炎球菌结合疫苗的引入降低了儿童的发病率，现在成人的患病率令人担忧。结论OM的经济负担在全球范围内相对较高，解决这一公共卫生负担很重要。预防方法，诊断,卫生系统应进行治疗，以减轻这种疾病负担。
