PDF(Pubmed)
Abstract：
UNASSIGNED: Potentially inappropriate medication (PIM) use is one of the main drug-related problems encountered in older adults. It is associated with adverse drug events, morbidity, mortality, increased economic costs, and negative effects on the quality of life that requires strict monitoring of prescriptions in older adults. Thus, the study aimed to assess potentially inappropriate medication use and its determinants among older adults.
UNASSIGNED: A cross-sectional study was conducted among all outpatient prescriptions dispensed to older adults (aged 65 years and above) in six community chain pharmacies in Asmara, Eritrea. Data were collected retrospectively, between June 16 and July 16, 2023. PIMs were detected using the 2023 American Geriatric Society (AGS) Beers Criteria®. Descriptive statistics and logistic regression analysis were performed using IBM SPSS® (Version-26.0).
UNASSIGNED: A total of 2680 outpatient prescriptions dispensed to older adults were included in this study. The prevalence of PIM among prescriptions was 18.1% (95% CI: 16.7, 19.6). Moreover, a total of 470 medications were found to be avoided in older adults. The most commonly prescribed PIMs were sulfonylureas (27.2%) and substituted alkylamines (16.2%). The prevalence of prescriptions containing medications to be used with caution in older adults was 13.2% (95% CI: 12.0, 14.5). Age (Adjusted Odds Ratio (AOR))=0.98, 95% CI: 0.97, 0.99), polypharmacy (AOR=2.77, 95% CI: 1.49, 5.15), and general practitioner prescriber (AOR=1.38, 95% CI: 1.11, 1.70) were significantly associated with PIMs.
UNASSIGNED: A considerable number of ambulatory older adults were exposed to PIMs which require a close attention by policymakers, program managers, and healthcare professionals.
UNASSIGNED: A cross-sectional study was conducted among all outpatient prescriptions dispensed to older adults (aged 65 years and above) in six community chain pharmacies in Asmara, Eritrea. Data were collected retrospectively, between June 16 and July 16, 2023. PIMs were detected using the 2023 American Geriatric Society (AGS) Beers Criteria®. Descriptive statistics and logistic regression analysis were performed using IBM SPSS® (Version-26.0).
UNASSIGNED: A total of 2680 outpatient prescriptions dispensed to older adults were included in this study. The prevalence of PIM among prescriptions was 18.1% (95% CI: 16.7, 19.6). Moreover, a total of 470 medications were found to be avoided in older adults. The most commonly prescribed PIMs were sulfonylureas (27.2%) and substituted alkylamines (16.2%). The prevalence of prescriptions containing medications to be used with caution in older adults was 13.2% (95% CI: 12.0, 14.5). Age (Adjusted Odds Ratio (AOR))=0.98, 95% CI: 0.97, 0.99), polypharmacy (AOR=2.77, 95% CI: 1.49, 5.15), and general practitioner prescriber (AOR=1.38, 95% CI: 1.11, 1.70) were significantly associated with PIMs.
UNASSIGNED: A considerable number of ambulatory older adults were exposed to PIMs which require a close attention by policymakers, program managers, and healthcare professionals.
摘要：
■潜在的不适当药物（PIM）使用是老年人遇到的主要药物相关问题之一。它与不良药物事件有关，发病率，死亡率,经济成本增加，以及对生活质量的负面影响，需要严格监测老年人的处方。因此，该研究旨在评估老年人中潜在的不适当用药及其决定因素.
■在阿斯马拉的六个社区连锁药店中，对分配给老年人（65岁及以上）的所有门诊处方进行了横断面研究，厄立特里亚。数据是回顾性收集的，2023年6月16日至7月16日。使用2023年美国老年医学会(AGS)啤酒标准®检测PIM。使用IBMSPSS®(Version-26.0)进行描述性统计和逻辑回归分析。
■这项研究共纳入了向老年人发放的2680张门诊处方。处方中PIM的患病率为18.1％（95％CI：16.7，19.6）。此外，在老年人中,共有470种药物被避免服用.最常用的PIM是磺酰脲类（27.2％）和取代的烷基胺（16.2％）。老年人中含有谨慎使用药物的处方的患病率为13.2%(95%CI:12.0,14.5)。年龄（调整后赔率比（AOR））=0.98，95%CI：0.97，0.99），复方药（AOR=2.77，95%CI：1.49，5.15），和全科医生处方（AOR=1.38，95％CI：1.11，1.70）与PIMs显着相关。
■相当数量的门诊老年人暴露于需要决策者密切关注的PIMs，项目经理,和医疗保健专业人员。
■在阿斯马拉的六个社区连锁药店中，对分配给老年人（65岁及以上）的所有门诊处方进行了横断面研究，厄立特里亚。数据是回顾性收集的，2023年6月16日至7月16日。使用2023年美国老年医学会(AGS)啤酒标准®检测PIM。使用IBMSPSS®(Version-26.0)进行描述性统计和逻辑回归分析。
■这项研究共纳入了向老年人发放的2680张门诊处方。处方中PIM的患病率为18.1％（95％CI：16.7，19.6）。此外，在老年人中,共有470种药物被避免服用.最常用的PIM是磺酰脲类（27.2％）和取代的烷基胺（16.2％）。老年人中含有谨慎使用药物的处方的患病率为13.2%(95%CI:12.0,14.5)。年龄（调整后赔率比（AOR））=0.98，95%CI：0.97，0.99），复方药（AOR=2.77，95%CI：1.49，5.15），和全科医生处方（AOR=1.38，95％CI：1.11，1.70）与PIMs显着相关。
■相当数量的门诊老年人暴露于需要决策者密切关注的PIMs，项目经理,和医疗保健专业人员。
