PDF(Pubmed)
Abstract：
UNASSIGNED: The disease burden of gestational diabetes mellitus (GDM) in sub-Saharan African region have been on the rise. Proper assessment of current prevalence of GDM may inform policy changes and management approach for improved care delivery.
UNASSIGNED: To determine the current prevalence of Gestational Diabetes Mellitus (GDM) and evaluate its major risk factors amongst pregnant women in Makurdi, North-Central Nigeria.
UNASSIGNED: This was a multi-center hospital-based prospective observational study. Maternal characteristics and clinical risk factors for GDM in a cohort of 281 pregnant women at 9 to 16 weeks gestational age was evaluated. The one-step 75g oral glucose tolerance test (OGTT) was carried out at 24 to 28 weeks of gestation.
UNASSIGNED: Of the 356 women recruited, 281 (79.8%) completed the study. The GDM prevalence in the cohort was 16.7%. Increased early pregnancy BMI (adjusted OR = 1.154, 95% CI = 1.080 - 1.233, p<0.001) and presence of family history of diabetes mellitus (adjusted OR = 0.482, 95% CI = 0.233 - 0.997, P<0.05) were independent risk factors for GDM in the cohort.
UNASSIGNED: Increasing maternal age and early pregnancy BMI amongst other possible reasons, may account for the rising prevalence of GDM in the region.
UNASSIGNED: To determine the current prevalence of Gestational Diabetes Mellitus (GDM) and evaluate its major risk factors amongst pregnant women in Makurdi, North-Central Nigeria.
UNASSIGNED: This was a multi-center hospital-based prospective observational study. Maternal characteristics and clinical risk factors for GDM in a cohort of 281 pregnant women at 9 to 16 weeks gestational age was evaluated. The one-step 75g oral glucose tolerance test (OGTT) was carried out at 24 to 28 weeks of gestation.
UNASSIGNED: Of the 356 women recruited, 281 (79.8%) completed the study. The GDM prevalence in the cohort was 16.7%. Increased early pregnancy BMI (adjusted OR = 1.154, 95% CI = 1.080 - 1.233, p<0.001) and presence of family history of diabetes mellitus (adjusted OR = 0.482, 95% CI = 0.233 - 0.997, P<0.05) were independent risk factors for GDM in the cohort.
UNASSIGNED: Increasing maternal age and early pregnancy BMI amongst other possible reasons, may account for the rising prevalence of GDM in the region.
摘要：
撒哈拉以南非洲地区妊娠期糖尿病（GDM）的疾病负担一直在上升。对GDM当前患病率的正确评估可能会为政策变更和管理方法提供信息，以改善护理服务。
■为了确定当前妊娠糖尿病（GDM）的患病率并评估其在Makurdi孕妇中的主要危险因素，尼日利亚中北部。
■这是一项基于多中心医院的前瞻性观察性研究。对281例孕龄9~16周孕妇的GDM的母体特征和临床危险因素进行了评估。在妊娠24至28周进行一步75g口服葡萄糖耐量试验（OGTT）。
■在被招募的356名女性中，281人（79.8%）完成研究。队列中GDM的患病率为16.7%。孕早期BMI升高（校正后OR=1.154，95%CI=1.080-1.233，p<0.001）和有糖尿病家族史（校正后OR=0.482，95%CI=0.233-0.997，P<0.05）是GDM的独立危险因素。
■在其他可能的原因中，增加产妇年龄和怀孕早期BMI，可能是该地区GDM患病率上升的原因。
■为了确定当前妊娠糖尿病（GDM）的患病率并评估其在Makurdi孕妇中的主要危险因素，尼日利亚中北部。
■这是一项基于多中心医院的前瞻性观察性研究。对281例孕龄9~16周孕妇的GDM的母体特征和临床危险因素进行了评估。在妊娠24至28周进行一步75g口服葡萄糖耐量试验（OGTT）。
■在被招募的356名女性中，281人（79.8%）完成研究。队列中GDM的患病率为16.7%。孕早期BMI升高（校正后OR=1.154，95%CI=1.080-1.233，p<0.001）和有糖尿病家族史（校正后OR=0.482，95%CI=0.233-0.997，P<0.05）是GDM的独立危险因素。
■在其他可能的原因中，增加产妇年龄和怀孕早期BMI，可能是该地区GDM患病率上升的原因。
