PDF(Pubmed)
Abstract：
UNASSIGNED: Long-term hyperglycemia can lead to changes in the function and morphology of platelets.
UNASSIGNED: This study aimed to test the potential glucoregulation monitoring properties of platelet indices, mean platelet volume (MPV) and platelet distribution width (PDW), in children with type 1 diabetes mellitus (T1DM).
UNASSIGNED: The study included 453 patients below the age of 18 with T1DM treated at the Institute for Child and Youth Health Care of Vojvodina. Children were divided into two groups, according to their glucoregulation quality, i.e., glycated hemoglobin (HbA1c) levels. Descriptive and inferential statistical analyses were performed.
UNASSIGNED: MPV and PDW were found to be important in predicting poor glucoregulation, both in independent and conjoint analysis. Proposed cut-off values for MPV and PDW in the glucose control monitoring of children with T1DM were 7.6 fL and 14.4%, respectively.
UNASSIGNED: Our study showed that MPV and PDW have monitoring properties in terms of glucose control in children with T1DM. Additionally, our study emphasizes the importance of selecting the most convenient control group in order to avoid misleading conclusions.
UNASSIGNED: This study aimed to test the potential glucoregulation monitoring properties of platelet indices, mean platelet volume (MPV) and platelet distribution width (PDW), in children with type 1 diabetes mellitus (T1DM).
UNASSIGNED: The study included 453 patients below the age of 18 with T1DM treated at the Institute for Child and Youth Health Care of Vojvodina. Children were divided into two groups, according to their glucoregulation quality, i.e., glycated hemoglobin (HbA1c) levels. Descriptive and inferential statistical analyses were performed.
UNASSIGNED: MPV and PDW were found to be important in predicting poor glucoregulation, both in independent and conjoint analysis. Proposed cut-off values for MPV and PDW in the glucose control monitoring of children with T1DM were 7.6 fL and 14.4%, respectively.
UNASSIGNED: Our study showed that MPV and PDW have monitoring properties in terms of glucose control in children with T1DM. Additionally, our study emphasizes the importance of selecting the most convenient control group in order to avoid misleading conclusions.
摘要：
■长期高血糖可导致血小板功能和形态的变化。
■本研究旨在测试血小板指标的潜在糖调节监测特性，平均血小板体积（MPV）和血小板分布宽度（PDW），儿童1型糖尿病（T1DM）。
该研究包括在伏伊伏丁那儿童和青年保健研究所接受治疗的453名18岁以下的T1DM患者。儿童被分为两组，根据它们的葡萄糖调节质量，即，糖化血红蛋白（HbA1c）水平。进行描述性和推断性统计分析。
■发现MPV和PDW在预测葡萄糖调节不良方面很重要，无论是在独立分析还是联合分析中。在T1DM儿童血糖控制监测中MPV和PDW的建议临界值分别为7.6fL和14.4％，分别。
■我们的研究表明，MPV和PDW在T1DM儿童的血糖控制方面具有监测特性。此外,我们的研究强调了选择最方便的对照组以避免误导性结论的重要性。
■本研究旨在测试血小板指标的潜在糖调节监测特性，平均血小板体积（MPV）和血小板分布宽度（PDW），儿童1型糖尿病（T1DM）。
该研究包括在伏伊伏丁那儿童和青年保健研究所接受治疗的453名18岁以下的T1DM患者。儿童被分为两组，根据它们的葡萄糖调节质量，即，糖化血红蛋白（HbA1c）水平。进行描述性和推断性统计分析。
■发现MPV和PDW在预测葡萄糖调节不良方面很重要，无论是在独立分析还是联合分析中。在T1DM儿童血糖控制监测中MPV和PDW的建议临界值分别为7.6fL和14.4％，分别。
■我们的研究表明，MPV和PDW在T1DM儿童的血糖控制方面具有监测特性。此外,我们的研究强调了选择最方便的对照组以避免误导性结论的重要性。
