UNASSIGNED: The present study aims at examining the association between dysmenorrhea severity and antihypertensives and analgesics namely acetaminophen and Non-Steroidal Anti-inflammatory Drugs (NSAIDs) used by traumatized Syrian war refugees with hypertension.
UNASSIGNED: This is a cross-sectional study recruiting Syrian female refugees with hypertension. A structured questionnaire probed their demographics and clinical data. Dysmenorrhea severity was assessed using the WaLIDD (working ability, location, intensity, days of pain, dysmenorrhea) self-report scale.
UNASSIGNED: Data were analysed from 125 patients, almost half were diabetic, 47 (37.6%) had dyslipidemia, 59 (47%) reported using β-blockers, 56 (44.8%) reported using ACEIs/ARBs, 43 (34.2) reported using CCBs and 30 (25%) were using diuretics. According to the multivariate binary logistic regression, severe dysmenorrhea was associated with acetaminophen OR 6.5, 95%CI (1.39-30.55), p=0.02 and NSAIDs use OR 2.97, 95%CI (1.28-6.89), p=0.02. Antihypertensive drugs were not associated with dysmenorrhea severity.
UNASSIGNED: Determinants of severe dysmenorrhea in patients with hypertension need more study, herein we report that analgesics but not antihypertensives are not associated with dysmenorrhea severity.
■本研究旨在研究痛经严重程度与抗高血压药和镇痛药(即对乙酰氨基酚和非甾体抗炎药(NSAIDs))之间的关系。
■这是一项招募患有高血压的叙利亚女性难民的横断面研究。结构化问卷调查了他们的人口统计学和临床数据。使用WaLIDD评估痛经严重程度(工作能力,location,强度,痛苦的日子,痛经)自我报告量表。
■分析了125名患者的数据,几乎一半是糖尿病患者,47人(37.6%)有血脂异常,59(47%)报告使用β受体阻滞剂,56(44.8%)使用ACEI/ARB报告,43例(34.2)使用CCB,30例(25%)使用利尿剂。根据多元二元逻辑回归,严重的痛经与对乙酰氨基酚OR6.5,95CI(1.39-30.55)有关,p=0.02,NSAIDs使用OR2.97,95CI(1.28-6.89),p=0.02。抗高血压药物与痛经严重程度无关。
■高血压患者严重痛经的决定因素需要更多的研究,本文我们报道了镇痛药而不是抗高血压药与痛经严重程度无关。