PDF(Pubmed)
Abstract：
UNASSIGNED: To use pharyngeal pressure recordings to distinguish different upper airway collapse patterns in obstructive sleep apnea (OSA) patients, and to assess whether these pressure recordings correlate with candidacy assessment for hypoglossal nerve stimulator (HGNS) implantation.
UNASSIGNED: Prospective case series.
UNASSIGNED: Single tertiary-quaternary care academic center.
UNASSIGNED: Subjects with OSA prospectively underwent simultaneous drug-induced sleep endoscopy (DISE) and transnasal pharyngeal pressure recording with a pressure-transducing catheter. Pressure was recorded in the nasopharynx and oropharynx, and endoscopic collapse patterns were classified based on site, extent, and direction of collapse. Pressure recordings were classified categorically by waveform shape as well as numerically by inspiratory and expiratory amplitudes and slopes. Waveform shape, amplitude, and slope were then compared with the endoscopic findings.
UNASSIGNED: Twenty-five subjects with OSA were included. Nasopharyngeal waveform shape was associated with the extent of collapse at the level of the palate (P = .001). Oropharyngeal waveform shape was associated with anatomical site of collapse (P < .001) and direction of collapse (P = .019) below the level of the palate. Pressure amplitudes and slopes were also associated with the extent of collapse at various sites. Waveform shape was also associated with favorable collapse pattern on endoscopy for HGNS implantation (P = .043), as well as surgical candidacy for HGNS (P = .004).
UNASSIGNED: Characteristic pharyngeal pressure waveforms are associated with different airway collapse patterns. Pharyngeal pressure is a promising adjunct to DISE in the sleep surgery candidacy evaluation.
UNASSIGNED: Prospective case series.
UNASSIGNED: Single tertiary-quaternary care academic center.
UNASSIGNED: Subjects with OSA prospectively underwent simultaneous drug-induced sleep endoscopy (DISE) and transnasal pharyngeal pressure recording with a pressure-transducing catheter. Pressure was recorded in the nasopharynx and oropharynx, and endoscopic collapse patterns were classified based on site, extent, and direction of collapse. Pressure recordings were classified categorically by waveform shape as well as numerically by inspiratory and expiratory amplitudes and slopes. Waveform shape, amplitude, and slope were then compared with the endoscopic findings.
UNASSIGNED: Twenty-five subjects with OSA were included. Nasopharyngeal waveform shape was associated with the extent of collapse at the level of the palate (P = .001). Oropharyngeal waveform shape was associated with anatomical site of collapse (P < .001) and direction of collapse (P = .019) below the level of the palate. Pressure amplitudes and slopes were also associated with the extent of collapse at various sites. Waveform shape was also associated with favorable collapse pattern on endoscopy for HGNS implantation (P = .043), as well as surgical candidacy for HGNS (P = .004).
UNASSIGNED: Characteristic pharyngeal pressure waveforms are associated with different airway collapse patterns. Pharyngeal pressure is a promising adjunct to DISE in the sleep surgery candidacy evaluation.
摘要：
■使用咽部压力记录来区分阻塞性睡眠呼吸暂停（OSA）患者的不同上呼吸道塌陷模式，并评估这些压力记录是否与舌下神经刺激器（HGNS）植入的候选性评估相关。
■前瞻性病例系列。
■单一三级护理学术中心。
■患有OSA的受试者前瞻性地同时接受药物诱导的睡眠内窥镜检查（DISE）和使用压力传感导管的经鼻咽部压力记录。记录鼻咽和口咽部的压力，内窥镜塌陷模式根据部位进行分类，范围,和崩溃的方向。压力记录按波形形状分类，并按吸气和呼气幅度和斜率进行数字分类。波形形状，振幅,然后将斜率与内镜检查结果进行比较。
■包括25名患有OSA的受试者。鼻咽波形形状与腭水平塌陷程度相关（P=0.001）。口咽波形形状与塌陷的解剖部位（P<.001）和塌陷方向（P=.019）相关。压力振幅和斜率也与不同地点的塌陷程度有关。波形形状也与HGNS植入内窥镜检查的良好塌陷模式相关（P=.043），以及HGNS的手术候选人资格（P=.004）。
■特征咽压波形与不同的气道塌陷模式相关。在睡眠手术候选人资格评估中，咽压是DISE的有希望的辅助手段。
■前瞻性病例系列。
■单一三级护理学术中心。
■患有OSA的受试者前瞻性地同时接受药物诱导的睡眠内窥镜检查（DISE）和使用压力传感导管的经鼻咽部压力记录。记录鼻咽和口咽部的压力，内窥镜塌陷模式根据部位进行分类，范围,和崩溃的方向。压力记录按波形形状分类，并按吸气和呼气幅度和斜率进行数字分类。波形形状，振幅,然后将斜率与内镜检查结果进行比较。
■包括25名患有OSA的受试者。鼻咽波形形状与腭水平塌陷程度相关（P=0.001）。口咽波形形状与塌陷的解剖部位（P<.001）和塌陷方向（P=.019）相关。压力振幅和斜率也与不同地点的塌陷程度有关。波形形状也与HGNS植入内窥镜检查的良好塌陷模式相关（P=.043），以及HGNS的手术候选人资格（P=.004）。
■特征咽压波形与不同的气道塌陷模式相关。在睡眠手术候选人资格评估中，咽压是DISE的有希望的辅助手段。
