PDF(Pubmed)
Abstract：
UNASSIGNED: Uterine artery embolization (UAE) and hysterectomy are often used to treat uterine myoma. Nevertheless, the impact of these two treatments on postoperative ovarian function remains uncertain.
UNASSIGNED: To compare the postoperative ovarian function in individuals with uterine myoma who had UAE against hysterectomy.
UNASSIGNED: Searches were conducted in the Wanfang, Web of Science, and PubMed databases to find qualifying studies. The data were combined and analyzed.
UNASSIGNED: Seven publications were included in this meta-analysis. Uterus and uterine myoma volume were dramatically decreased by UAE (p < 0.00001 for both). The combined preoperative levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) were similar in both groups. Three months postoperatively, the combined FSH (p = 0.28) and LH (p = 0.64) levels were similar in both groups, while the combined E2 level was notably higher in the UAE group compared to the hysterectomy group (p < 0.00001). Six months postoperatively, the combined postoperative FSH and LH levels were considerably lower in the UAE group compared to the hysterectomy group (p = 0.002 for both). However, the combined E2 levels were similar between the two groups (p = 0.07). Also, 12 months after surgery, the combined postoperative FSH and LH levels were remarkably lower in the UAE group compared to the hysterectomy group (p = 0.02 and p < 0.00001, respectively). However, the combined E2 levels were similar in both groups (p = 0.15).
UNASSIGNED: UAE may provide superior preservation of postoperative ovarian function compared to hysterectomy in individuals with uterine myoma.
UNASSIGNED: To compare the postoperative ovarian function in individuals with uterine myoma who had UAE against hysterectomy.
UNASSIGNED: Searches were conducted in the Wanfang, Web of Science, and PubMed databases to find qualifying studies. The data were combined and analyzed.
UNASSIGNED: Seven publications were included in this meta-analysis. Uterus and uterine myoma volume were dramatically decreased by UAE (p < 0.00001 for both). The combined preoperative levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) were similar in both groups. Three months postoperatively, the combined FSH (p = 0.28) and LH (p = 0.64) levels were similar in both groups, while the combined E2 level was notably higher in the UAE group compared to the hysterectomy group (p < 0.00001). Six months postoperatively, the combined postoperative FSH and LH levels were considerably lower in the UAE group compared to the hysterectomy group (p = 0.002 for both). However, the combined E2 levels were similar between the two groups (p = 0.07). Also, 12 months after surgery, the combined postoperative FSH and LH levels were remarkably lower in the UAE group compared to the hysterectomy group (p = 0.02 and p < 0.00001, respectively). However, the combined E2 levels were similar in both groups (p = 0.15).
UNASSIGNED: UAE may provide superior preservation of postoperative ovarian function compared to hysterectomy in individuals with uterine myoma.
摘要：
■子宫动脉栓塞术（UAE）和子宫切除术通常用于治疗子宫肌瘤。然而，这两种治疗方法对术后卵巢功能的影响尚不确定.
■比较UAE反对子宫切除术的子宫肌瘤患者术后卵巢功能。
■在万方进行了搜索，WebofScience,和PubMed数据库来查找合格的研究。将数据进行合并和分析。
■本荟萃分析包括7篇出版物。子宫和子宫肌瘤体积通过UAE显著减少(两者p<0.00001)。术前联合卵泡刺激素(FSH)水平,黄体生成素(LH),和雌二醇（E2）在两组中相似。术后三个月,两组的FSH（p=0.28）和LH（p=0.64）水平相似，而联合E2水平在UAE组明显高于子宫切除术组(p<0.00001).术后六个月,与子宫切除术组相比,UAE组术后FSH和LH的综合水平显著降低(两者的p=0.002).然而,两组间合并E2水平相似(p=0.07).此外，手术后12个月,与子宫切除术组相比,UAE组术后FSH和LH水平显著降低(分别为p=0.02和p<0.00001).然而,两组的合并E2水平相似(p=0.15).
■在子宫肌瘤患者中，与子宫切除术相比，UAE可以更好地保护术后卵巢功能。
■比较UAE反对子宫切除术的子宫肌瘤患者术后卵巢功能。
■在万方进行了搜索，WebofScience,和PubMed数据库来查找合格的研究。将数据进行合并和分析。
■本荟萃分析包括7篇出版物。子宫和子宫肌瘤体积通过UAE显著减少(两者p<0.00001)。术前联合卵泡刺激素(FSH)水平,黄体生成素(LH),和雌二醇（E2）在两组中相似。术后三个月,两组的FSH（p=0.28）和LH（p=0.64）水平相似，而联合E2水平在UAE组明显高于子宫切除术组(p<0.00001).术后六个月,与子宫切除术组相比,UAE组术后FSH和LH的综合水平显著降低(两者的p=0.002).然而,两组间合并E2水平相似(p=0.07).此外，手术后12个月,与子宫切除术组相比,UAE组术后FSH和LH水平显著降低(分别为p=0.02和p<0.00001).然而,两组的合并E2水平相似(p=0.15).
■在子宫肌瘤患者中，与子宫切除术相比，UAE可以更好地保护术后卵巢功能。
