{Reference Type}: Journal Article {Title}: Uterine artery embolization versus hysterectomy for uterine myoma: a meta-analysis of postoperative ovarian function. {Author}: Li L;Liu Y;Wang S; {Journal}: Wideochir Inne Tech Maloinwazyjne {Volume}: 19 {Issue}: 2 {Year}: 2024 Jun {Factor}: 1.627 {DOI}: 10.5114/wiitm.2024.138767 {Abstract}: UNASSIGNED: Uterine artery embolization (UAE) and hysterectomy are often used to treat uterine myoma. Nevertheless, the impact of these two treatments on postoperative ovarian function remains uncertain.
UNASSIGNED: To compare the postoperative ovarian function in individuals with uterine myoma who had UAE against hysterectomy.
UNASSIGNED: Searches were conducted in the Wanfang, Web of Science, and PubMed databases to find qualifying studies. The data were combined and analyzed.
UNASSIGNED: Seven publications were included in this meta-analysis. Uterus and uterine myoma volume were dramatically decreased by UAE (p < 0.00001 for both). The combined preoperative levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) were similar in both groups. Three months postoperatively, the combined FSH (p = 0.28) and LH (p = 0.64) levels were similar in both groups, while the combined E2 level was notably higher in the UAE group compared to the hysterectomy group (p < 0.00001). Six months postoperatively, the combined postoperative FSH and LH levels were considerably lower in the UAE group compared to the hysterectomy group (p = 0.002 for both). However, the combined E2 levels were similar between the two groups (p = 0.07). Also, 12 months after surgery, the combined postoperative FSH and LH levels were remarkably lower in the UAE group compared to the hysterectomy group (p = 0.02 and p < 0.00001, respectively). However, the combined E2 levels were similar in both groups (p = 0.15).
UNASSIGNED: UAE may provide superior preservation of postoperative ovarian function compared to hysterectomy in individuals with uterine myoma.