Abstract:
The Victorian Government introduced a time-limited human papillomavirus (HPV) catch-up program for gay, bisexual, and other men who have sex with men (GBMSM) aged ≤ 26 years in 2017-2019. We conducted a retrospective observational study to examine the accuracy of the self-report of HPV vaccination status using computer-assisted self-interviewing versus their immunization history via electronic health records. We included GBMSM aged 23-30 years visiting the Melbourne Sexual Health Centre (MSHC) in 2020-2021 because they were age-eligible for the HPV catch-up program in Victoria, Australia. Individuals who were unsure about their vaccination status were categorized as \'unvaccinated\'. Of the 1,786 eligible men, 1,665 men self-reported their HPV vaccination status: 48.8% (n = 812) vaccinated, 17.4% (n = 289) unvaccinated, and 33.9% (n = 564) unsure. Self-reported HPV vaccination had a sensitivity of 61.3% (95%CI: 58.3 to 64.2%; 661/1079), a specificity of 74.2% (95%CI: 70.5 to 77.7%; 435/586), a positive predictive value of 81.4% (95%CI: 78.6 to 84.0%; 661/812), a negative predictive value of 51.0% (95%CI: 47.6 to 54.4%; 435/853), and an accuracy of 52.6% (95%CI: 50.1 to 55.0%). Our results showed that only half of GBMSM know and report their HPV vaccination status correctly. Novel approaches such as digital vaccine passports may be useful for individuals to accurately report their vaccination status to guide accurate clinical decisions and management.
摘要:
维多利亚州政府推出了一项针对同性恋的限时人类乳头瘤病毒(HPV)追赶计划,双性恋,以及2017-2019年年龄≤26岁的其他男男性行为者(GBMSM)。我们进行了一项回顾性观察研究,以检查使用计算机辅助自我访谈与通过电子健康记录的免疫史的HPV疫苗接种状态的自我报告的准确性。我们纳入了年龄在23-30岁之间的GBMSM,他们在2020-2021年访问了墨尔本性健康中心(MSHC),因为他们符合维多利亚州HPV追赶计划的年龄。澳大利亚。不确定其疫苗接种状态的个人被归类为“未接种疫苗”。在1,786名合格男子中,1665名男性自我报告他们的HPV疫苗接种状态:48.8%(n=812)接种疫苗,17.4%(n=289)未接种疫苗,33.9%(n=564)不确定。自我报告的HPV疫苗的敏感性为61.3%(95CI:58.3至64.2%;661/1079),特异性为74.2%(95CI:70.5至77.7%;435/586),阳性预测值为81.4%(95CI:78.6至84.0%;661/812),阴性预测值为51.0%(95CI:47.6至54.4%;435/853),准确率为52.6%(95CI:50.1%至55.0%)。我们的结果表明,只有一半的GBMSM正确知道并报告了他们的HPV疫苗接种状况。数字疫苗护照等新方法可能有助于个人准确报告其疫苗接种状态,以指导准确的临床决策和管理。