Abstract：
Acute sleep deprivation in experimental studies has been shown to induce pain hypersensitivity in females. However, the impact of natural sleep deficiency and fluctuations across the week on pain perception remains unclear. A sleep-monitoring headband and self-reports were utilized to assess objective and subjective sleep in longer (> 6 hr) and short sleepers (< 6 hr). Pain sensitivity measures including heat, cold, pressure pain thresholds, pain inhibition (conditioned pain modulation) and facilitation (tonic pain summation) were assessed on Mondays and Fridays. Forty-one healthy young (23.9 ± 0.74 years) women participated. Short sleepers slept on average 2 hr less than longer sleepers (297.9 ± 8.2 min versus 418.5 ± 10.9 min) and experienced impaired pain inhibitory response (mean = -21.14 ± 7.9°C versus mean = 15.39 ± 9.5°C; p = 0.005). However, no effect was observed in pain thresholds and pain summation (p > 0.05). Furthermore, pain modulatory responses differed between Mondays and Fridays. Chronic sleep deficiency (< 6 hr) compromises pain responses, notably on Mondays. Maintaining a consistent sleep pattern with sufficient sleep (> 6 hr) throughout the week may protect against pain sensitization and the development of chronic pain in females. Further research is needed, especially in patients with chronic pain.
摘要：
实验研究表明，急性睡眠剥夺会引起女性的疼痛过敏。然而,自然睡眠不足和一周内波动对疼痛感知的影响尚不清楚.使用睡眠监测头带和自我报告来评估较长（>6小时）和短睡眠（<6小时）的客观和主观睡眠。疼痛敏感性措施，包括热，冷,压力疼痛阈值，在周一和周五评估疼痛抑制(条件性疼痛调节)和促进(强直性疼痛总和).41名健康的年轻（23.9±0.74岁）妇女参加了比赛。短睡眠者的平均睡眠时间比长睡眠者少2小时（297.9±8.2分钟对418.5±10.9分钟），并且疼痛抑制反应受损（平均值=-21.14±7.9°C，平均值=15.39±9.5°C；p=0.005）。然而,在疼痛阈值和疼痛总和方面没有观察到影响(p>0.05)。此外，周一和周五的疼痛调节反应不同。慢性睡眠不足（<6小时）会损害疼痛反应，尤其是周一。在整个星期内保持一致的睡眠模式和充足的睡眠(>6小时)可以防止女性的疼痛致敏和慢性疼痛的发展。需要进一步的研究,尤其是慢性疼痛患者。
