从刺五加皮提取物中鉴定木脂素作为选择性环氧合酶 - 2 抑制剂。
关键词: Acanthopanacis cortex Araliaceae Cyclooxygenase-1 Cyclooxygenase-2 Lignans Neutrophil elastase
Mesh : Lignans / pharmacology chemistry isolation & purification Cyclooxygenase 2 Inhibitors / pharmacology chemistry isolation & purification Eleutherococcus / chemistry Molecular Structure Cyclooxygenase 2 / metabolism Structure-Activity Relationship Cyclooxygenase 1 / metabolism Leukocyte Elastase / antagonists & inhibitors metabolism Dose-Response Relationship, Drug Plant Bark / chemistry Humans Plant Extracts / pharmacology chemistry isolation & purification Plant Roots / chemistry
来 源: DOI:10.1016/j.phytochem.2024.114208