Abstract：
BACKGROUND: Vestibular schwannoma (VS) is a benign tumor of the vestibular nerve. Flair-attenuated inversion recovery (FLAIR) of magnetic resonance imaging (MRI) images are sensitive in detecting high protein contents of fluids.
OBJECTIVE: To investigate the association between signal intensity (SI) on FLAIR images and audiovestibular findings in patients with VS.
METHODS: Medical records of twenty-five patients with VS were retrospectively analyzed.
RESULTS: Larger tumors were associated with increased FLAIR SI of the cochlea, vestibule, and semicircular canal (SCC) on the affected side compared to those of the unaffected side. Pure-tone audiometry (PTA), and speech audiometry were associated with the SI of the affected cochlea. There was no significant correlation between the SI of the vestibule and vestibular evoked myogenic potential, SI of the SCC, and caloric test or video head impulse test results.
CONCLUSIONS: Our study suggests that tumor size was significantly associated with high SI on FLAIR imaging, and audiological findings were associated with the SI of the affected cochlea. Further studies with larger cohorts are required to confirm the association between vestibular function and FLAIR imaging in VS.
OBJECTIVE: To investigate the association between signal intensity (SI) on FLAIR images and audiovestibular findings in patients with VS.
METHODS: Medical records of twenty-five patients with VS were retrospectively analyzed.
RESULTS: Larger tumors were associated with increased FLAIR SI of the cochlea, vestibule, and semicircular canal (SCC) on the affected side compared to those of the unaffected side. Pure-tone audiometry (PTA), and speech audiometry were associated with the SI of the affected cochlea. There was no significant correlation between the SI of the vestibule and vestibular evoked myogenic potential, SI of the SCC, and caloric test or video head impulse test results.
CONCLUSIONS: Our study suggests that tumor size was significantly associated with high SI on FLAIR imaging, and audiological findings were associated with the SI of the affected cochlea. Further studies with larger cohorts are required to confirm the association between vestibular function and FLAIR imaging in VS.
摘要：
背景：前庭神经鞘瘤（VS）是前庭神经的良性肿瘤。磁共振成像（MRI）图像的Flair衰减反转恢复（FLAIR）对检测流体中的高蛋白含量很敏感。
目的：研究VS患者FLAIR图像上的信号强度（SI）与听前庭表现之间的关系。
方法：对25例VS患者的病历进行回顾性分析。
结果：较大的肿瘤与耳蜗的FLAIRSI增加有关，前庭,患侧和半规管（SCC）与未患侧相比。纯音测听法（PTA），言语测听与受影响的耳蜗SI相关。前庭SI与前庭诱发肌源性电位无显著相关性,SCC的SI，和热量测试或视频头脉冲测试结果。
结论：我们的研究表明，FLAIR成像显示肿瘤大小与高SI显著相关，听力学发现与受影响的耳蜗SI相关。需要进行更大队列的进一步研究，以确认VS中前庭功能与FLAIR成像之间的关联。
目的：研究VS患者FLAIR图像上的信号强度（SI）与听前庭表现之间的关系。
方法：对25例VS患者的病历进行回顾性分析。
结果：较大的肿瘤与耳蜗的FLAIRSI增加有关，前庭,患侧和半规管（SCC）与未患侧相比。纯音测听法（PTA），言语测听与受影响的耳蜗SI相关。前庭SI与前庭诱发肌源性电位无显著相关性,SCC的SI，和热量测试或视频头脉冲测试结果。
结论：我们的研究表明，FLAIR成像显示肿瘤大小与高SI显著相关，听力学发现与受影响的耳蜗SI相关。需要进行更大队列的进一步研究，以确认VS中前庭功能与FLAIR成像之间的关联。
