Abstract:
The relationship between different ribonucleic acids (RNAs) and tumor immunity has been widely investigated. However, a systematic description of tumor immune-related RNAs in different tumors is still lacking. We collected the relationship of tumor immune-related RNAs from the published literature and presented them in a user-friendly interface, \"ImmRNA\" (http://www.immrna.cn/), to provide a resource to study immune-RNA-cancer regulatory relations. The ImmRNA contains 49 996 curated entries. Each entry includes gene symbols, gene types, target genes, downstream effects, functions, immune cells, and other information. By rearranging and reanalyzing the data, our dataset contains the following key points: (i) providing the links between RNAs and the immune in cancers, (ii) displaying the downstream effects and functions of RNAs, (iii) listing immune cells and immune pathways related to RNA function, (iv) showing the relationship between RNAs and prognostic outcomes, and (v) exhibiting the experimental methods described in the article. ImmRNA provides a valuable resource for understanding the functions of tumor immune-related RNAs. Database URL: http://www.immrna.cn/.
摘要:
已广泛研究了不同核糖核酸(RNA)与肿瘤免疫之间的关系。然而,目前尚缺乏对不同肿瘤中肿瘤免疫相关RNA的系统描述.我们从已发表的文献中收集了肿瘤免疫相关RNA的关系,并在用户友好的界面中呈现它们。\"ImmRNA\"(http://www.immrna.cn/),提供研究免疫-RNA-癌症调控关系的资源。ImmRNA包含49996个精选条目。每个条目都包括基因符号,基因类型,靶基因,下游效应,功能,免疫细胞,和其他信息。通过重新排列和重新分析数据,我们的数据集包含以下关键点:(i)提供RNA与癌症免疫之间的联系,(ii)展示RNA的下游效应和功能,(iii)列出与RNA功能相关的免疫细胞和免疫途径,(iv)显示RNA与预后结果之间的关系,和(v)展示本文所述的实验方法。ImmRNA为理解肿瘤免疫相关RNA的功能提供了宝贵的资源。数据库URL:http://www。immrna.cn/.