关键词: Definition Moderate Psoriatic arthritis Review Survey

来  源:   DOI:10.1007/s00296-024-05644-y

Abstract:
Evidence-based treatment recommendations for psoriatic arthritis (PsA) suggest that treatment should be individualised but acknowledge the difficulty of correctly defining levels of activity (mild, moderate and severe). The aim of this study was to define the parameters or disease characteristics that should be included in a future definition of moderate PsA. Mixed. methods: (1) literature review to identify previous assessment tools used to classify patients into mild, moderate and severe forms, and (2) survey of rheumatologists, and experts in PsA, to obtain their opinion on the degree of validation and applicability of published definitions and tools, and on the parameters that should be included in a future definition of moderate PsA. We propose eight domains/items to be included in a definition of moderate PsA: number of active joints and inflamed entheses, physician global assessment (by visual analogue scale), dactylitis, body surface area (BSA) affected by psoriasis, psoriasis in special locations, and absence of hip involvement. The Disease Activity Index for Psoriatic Arthritis (DAPSA) score would be supported as part of this definition, as would the Psoriatic Arthritis Impact of Disease (PsAID) index. This study proposes a set of items/domains to be included in a definition of moderate PsA based on literature and expert opinion, which can be the starting point for further development and validation studies of the proposed items.
摘要:
银屑病关节炎(PsA)的循证治疗建议建议应个体化治疗,但承认正确定义活动水平的困难(轻度,中度和重度)。这项研究的目的是定义未来中度PsA定义中应包括的参数或疾病特征。混合。方法:(1)文献综述,以确定以前用于将患者分为轻度,中度和重度形式,和(2)风湿病学家的调查,和PsA的专家,获得他们对已发布的定义和工具的验证程度和适用性的意见,以及未来适度PsA定义中应包含的参数。我们建议在中度PsA的定义中包含八个域/项目:活动关节和发炎的关节数量,医生全球评估(通过视觉模拟量表),牙龈炎,受银屑病影响的体表面积(BSA),牛皮癣在特殊的地方,没有髋关节受累.Psoriatic关节炎的疾病活动指数(DAPSA)评分将作为该定义的一部分得到支持。Psoriatic关节炎对疾病的影响(PsAID)指数也是如此。本研究根据文献和专家意见提出了一组项目/领域,将其纳入中度PsA的定义中。这可以作为进一步开发和验证研究的起点。
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