Abstract：
In this work, we developed a fast and straightforward colorimetric and photoluminescent chemosensor probe (P1), featuring bis-thiophene-thiosemicarbazide moieties as its signaling and binding unit. This probe exhibited rapid sensitivity to Hg2+ and Cu2+ ions in a semi-aqueous medium, resulting in distinct colorimetric and photoluminescent changes. In the presence of Cu2+, P1 displayed an impressive 50-fold increase in photoluminescence (PL) at 450 nm (with excitation at 365 nm). The probe P1 formed a 1:1 complex with Hg2+ and Cu2+ ions, featuring association constant values of 4.04 × 104 M-1 and 1.25 × 103 M-1, respectively. P1 has demonstrated its efficacy in the analysis of real samples, yielding promising results. Additionally, the probe successfully visualized copper ions on a mouse fibroblast cell line (NIH3T3), highlighting its potential as an intracellular probe for copper ion detection.
摘要：
在这项工作中,我们开发了一种快速直接的比色和光致发光化学传感器探针（P1），以双噻吩-氨基硫脲部分作为其信号传导和结合单位。该探针对半水介质中的Hg2和Cu2离子具有快速敏感性，导致明显的比色和光致发光变化。在Cu2+的存在下,P1在450nm处（在365nm处激发）显示出令人印象深刻的50倍光致发光（PL）增加。探针P1与Hg2+和Cu2+离子形成1:1复合物,具有关联常数值分别为4.04×104M-1和1.25×103M-1。P1已经证明了它在真实样本分析中的功效，产生有希望的结果。此外,该探针成功地显示了小鼠成纤维细胞系（NIH3T3）上的铜离子，突出了其作为铜离子检测细胞内探针的潜力。
