关键词: choriocarcinoma syndrome extracorporeal membrane oxygenation reduced chemotherapy respiratory failure resticular tumor

来  源:   DOI:10.1002/iju5.12725   PDF(Pubmed)

Abstract:
UNASSIGNED: Choriocarcinoma syndrome with multiple lung metastases has a poor prognosis and causes respiratory failure due to alveolar hemorrhage. We encountered a case where the introduction of extracorporeal membrane oxygenation effectively sustained oxygenation until chemotherapy took effect on lung metastases of testicular tumors.
UNASSIGNED: A 35-year-old man with dyspnea was referred to our hospital. He showed left testicular tumor with multiple lung metastases. Serum human chorionic gonadotropin level was also elevated. Reduced chemotherapy was initiated and extracorporeal membrane oxygenation was administered because of low oxygen levels on the fourth day. Chemotherapy successfully reduced the size of the lung masses, and extracorporeal membrane oxygenation was discontinued. Respiratory status improved substantially, but the patient died of brain metastases 4 months later.
UNASSIGNED: Extracorporeal membrane oxygenation may be a useful option for managing respiratory failure resulting from choriocarcinoma syndrome until the respiratory condition is improved by chemotherapy for testicular tumors.
摘要:
绒毛膜癌综合征伴多发性肺转移预后不良,并因肺泡出血导致呼吸衰竭。我们遇到了一个案例,其中引入体外膜氧合可有效维持氧合,直到化疗对睾丸肿瘤的肺转移产生影响。
一名35岁的呼吸困难患者被转诊到我们医院。左侧睾丸肿瘤伴多发肺转移。血清人绒毛膜促性腺激素水平也升高。由于第四天的低氧水平,开始减少化疗并进行体外膜氧合。化疗成功缩小了肺部肿块的大小,停止体外膜氧合。呼吸状态明显改善,但4个月后患者死于脑转移。
体外膜氧合可能是治疗绒毛膜癌综合征引起的呼吸衰竭的一个有用选择,直到睾丸肿瘤的化疗改善呼吸状况。
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