PDF(Pubmed)
Abstract：
UNASSIGNED: Sociodemographic disparities in genitourinary cancer-related mortality have been insufficiently studied, particularly across multiple cancer types. This study aimed to investigate gender, racial, and geographic disparities in mortality rates for the most common genitourinary cancers in the United States.
UNASSIGNED: Mortality data for prostate, bladder, kidney, and testicular cancers were obtained from the Centers for Disease Control and Prevention (CDC) WONDER database between 1999 and 2020. Age-adjusted mortality rates (AAMRs) were analyzed by year, gender, race, urban-rural status, and geographic region using a significance level of p < 0.05.
UNASSIGNED: Overall, AAMRs for prostate, bladder, and kidney cancer declined significantly, while testicular cancer-related mortality remained stable. Bladder and kidney cancer AAMRs were 3-4 times higher in males than females. Prostate cancer mortality was highest in black individuals/African Americans and began increasing after 2015. Bladder cancer mortality decreased significantly in White individuals, Black individuals, African Americans, and Asians/Pacific Islanders but remained stable in American Indian/Alaska Natives. Kidney cancer-related mortality was highest in White individuals but declined significantly in other races. Testicular cancer mortality increased significantly in White individuals but remained stable in Black individuals and African Americans. Genitourinary cancer mortality decreased in metropolitan areas but either increased (bladder and testicular cancer) or remained stable (kidney cancer) in non-metropolitan areas. Prostate and kidney cancer mortality was highest in the Midwest, bladder cancer in the South, and testicular cancer in the West.
UNASSIGNED: Significant sociodemographic disparities exist in the mortality trends of genitourinary cancers in the United States. These findings highlight the need for targeted interventions and further research to address these disparities and improve outcomes for all populations affected by genitourinary cancers.
UNASSIGNED: Mortality data for prostate, bladder, kidney, and testicular cancers were obtained from the Centers for Disease Control and Prevention (CDC) WONDER database between 1999 and 2020. Age-adjusted mortality rates (AAMRs) were analyzed by year, gender, race, urban-rural status, and geographic region using a significance level of p < 0.05.
UNASSIGNED: Overall, AAMRs for prostate, bladder, and kidney cancer declined significantly, while testicular cancer-related mortality remained stable. Bladder and kidney cancer AAMRs were 3-4 times higher in males than females. Prostate cancer mortality was highest in black individuals/African Americans and began increasing after 2015. Bladder cancer mortality decreased significantly in White individuals, Black individuals, African Americans, and Asians/Pacific Islanders but remained stable in American Indian/Alaska Natives. Kidney cancer-related mortality was highest in White individuals but declined significantly in other races. Testicular cancer mortality increased significantly in White individuals but remained stable in Black individuals and African Americans. Genitourinary cancer mortality decreased in metropolitan areas but either increased (bladder and testicular cancer) or remained stable (kidney cancer) in non-metropolitan areas. Prostate and kidney cancer mortality was highest in the Midwest, bladder cancer in the South, and testicular cancer in the West.
UNASSIGNED: Significant sociodemographic disparities exist in the mortality trends of genitourinary cancers in the United States. These findings highlight the need for targeted interventions and further research to address these disparities and improve outcomes for all populations affected by genitourinary cancers.
摘要：
■泌尿生殖系统癌症相关死亡率的社会人口统计学差异尚未得到充分研究，特别是在多种癌症类型中。本研究旨在调查性别，种族,以及美国最常见的泌尿生殖系统癌症死亡率的地理差异。
■前列腺死亡率数据，膀胱,肾,和睾丸癌从疾病控制和预防中心（CDC）WONDER数据库在1999年至2020年之间获得。按年份分析了年龄调整后的死亡率（AAMR），性别,种族,城乡地位，和地理区域使用P<0.05的显著性水平。
■总的来说，用于前列腺的AAMR，膀胱,肾癌显著下降，而睾丸癌相关死亡率保持稳定.膀胱和肾癌AAMR男性比女性高3-4倍。前列腺癌死亡率在黑人/非裔美国人中最高，2015年后开始增加。白种人膀胱癌死亡率显著下降，黑人个体,非洲裔美国人,和亚洲人/太平洋岛民，但在美洲印第安人/阿拉斯加原住民中保持稳定。与肾癌相关的死亡率在白人中最高，但在其他种族中显着下降。白人的睾丸癌死亡率显着增加，但黑人和非裔美国人保持稳定。大城市地区的泌尿生殖系统癌症死亡率下降，但在非大城市地区增加（膀胱癌和睾丸癌）或保持稳定（肾癌）。前列腺癌和肾癌死亡率在中西部最高，南方的膀胱癌,西方的睾丸癌.
■在美国泌尿生殖系统癌症的死亡率趋势中存在显著的社会人口统计学差异。这些发现强调了有针对性的干预措施和进一步研究的必要性，以解决这些差异并改善所有受泌尿生殖系统癌症影响的人群的结果。
■前列腺死亡率数据，膀胱,肾,和睾丸癌从疾病控制和预防中心（CDC）WONDER数据库在1999年至2020年之间获得。按年份分析了年龄调整后的死亡率（AAMR），性别,种族,城乡地位，和地理区域使用P<0.05的显著性水平。
■总的来说，用于前列腺的AAMR，膀胱,肾癌显著下降，而睾丸癌相关死亡率保持稳定.膀胱和肾癌AAMR男性比女性高3-4倍。前列腺癌死亡率在黑人/非裔美国人中最高，2015年后开始增加。白种人膀胱癌死亡率显著下降，黑人个体,非洲裔美国人,和亚洲人/太平洋岛民，但在美洲印第安人/阿拉斯加原住民中保持稳定。与肾癌相关的死亡率在白人中最高，但在其他种族中显着下降。白人的睾丸癌死亡率显着增加，但黑人和非裔美国人保持稳定。大城市地区的泌尿生殖系统癌症死亡率下降，但在非大城市地区增加（膀胱癌和睾丸癌）或保持稳定（肾癌）。前列腺癌和肾癌死亡率在中西部最高，南方的膀胱癌,西方的睾丸癌.
■在美国泌尿生殖系统癌症的死亡率趋势中存在显著的社会人口统计学差异。这些发现强调了有针对性的干预措施和进一步研究的必要性，以解决这些差异并改善所有受泌尿生殖系统癌症影响的人群的结果。
