PDF(Pubmed)
Abstract：
Whole genome sequencing (WGS) and data concerning identity and safety for Saccharomyces cerevisiae CBS 493.94 are reported. This strain was isolated from a British brewery in 1958 and deposited at the CBS culture collection Westerdijk Fungal Biodiversity Institute under the accession number CBS 493.94. The long-reads sequencing data, obtained via PacBio Sequel, and short-reads data, via Illumina NovaSeq 6000, were deposited at NCBI under accession number PRJNA1044661. The hybrid assembly was made publicly available via Zenodo and NCBI. For strain identification, data from 18S rRNA, ANI dendrogram and Core Genome single nucleotide polymorphism (SNP) Tree showed that the present isolate belongs to the genus Saccharomyces, species cerevisiae. The potential genes of concern, e.g. antimycotic resestance genes, were not detected. This strain is commonly used as a feed additive for animal health improvement and the present data summarise the unambiguous identity and strain\'s FKS1 gene does not code for any amino acid variants of concern.
摘要：
报道了酿酒酵母CBS493.94的全基因组测序（WGS）和有关身份和安全性的数据。该菌株于1958年从英国啤酒厂中分离出来，并以CBS493.94号保藏在CBS培养物Westerdijk真菌生物多样性研究所。长读数测序数据，通过PacBioSequel获得，和短读数据，通过IlluminaNovaSeq6000，以登录号PRJNA1044661存入NCBI。混合动力组件已通过Zenodo和NCBI公开提供。对于应变识别，来自18SrRNA的数据，ANI树状图和核心基因组单核苷酸多态性（SNP）树表明，本分离株属于酵母属，酿酒物种。潜在的关注基因，例如抗真菌基因，未检测到。该菌株通常用作改善动物健康的饲料添加剂，目前的数据总结了明确的身份，并且菌株的FKS1基因不编码任何令人关注的氨基酸变体。
