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Abstract：
Obesity is a global health concern that has been increasing over the years, and it is associated with several pathophysiological changes affecting the respiratory system, including alveolar hypoventilation. Obesity hypoventilation syndrome (OHS) is one of the six subtypes of sleep-hypoventilation disorders. It is defined as the presence of obesity, chronic alveolar hypoventilation leading to daytime hypercapnia and hypoxia, and sleep-disordered breathing. The existence of a sleep disorder is one of the characteristics that patients with OHS present. Among them, 90% of patients have obstructive sleep apnea (OSA), and the remaining 10% of patients with OHS have non-obstructive sleep hypoventilation without OSA or with mild OSA. This review aims to provide a comprehensive understanding of the epidemiological and pathophysiological impact of OHS and to highlight its clinical features, prognosis, and severity, as well as the available treatment options.
摘要：
肥胖是一个全球健康问题，多年来一直在增加，它与影响呼吸系统的几种病理生理变化有关，包括肺泡通气不足。肥胖通气不足综合征（OHS）是睡眠通气不足障碍的六种亚型之一。它被定义为肥胖的存在，慢性肺泡通气不足导致日间高碳酸血症和缺氧，和睡眠呼吸紊乱。睡眠障碍的存在是OHS患者存在的特征之一。其中,90％的患者患有阻塞性睡眠呼吸暂停（OSA），其余10％的OHS患者在无OSA或轻度OSA的情况下存在非阻塞性睡眠通气不足。这篇综述旨在全面了解OHS的流行病学和病理生理影响，并强调其临床特征。预后,和严重性，以及可用的治疗方案。
