%0 Journal Article %T Obesity hypoventilation syndrome, literature review. %A Orozco González BN %A Rodriguez Plascencia N %A Palma Zapata JA %A Llamas Domínguez AE %A Rodríguez González JS %A Diaz JM %A Ponce Muñoz M %A Ponce-Campos SD %J Sleep Adv %V 5 %N 1 %D 2024 %M 38966619 暂无%R 10.1093/sleepadvances/zpae033 %X Obesity is a global health concern that has been increasing over the years, and it is associated with several pathophysiological changes affecting the respiratory system, including alveolar hypoventilation. Obesity hypoventilation syndrome (OHS) is one of the six subtypes of sleep-hypoventilation disorders. It is defined as the presence of obesity, chronic alveolar hypoventilation leading to daytime hypercapnia and hypoxia, and sleep-disordered breathing. The existence of a sleep disorder is one of the characteristics that patients with OHS present. Among them, 90% of patients have obstructive sleep apnea (OSA), and the remaining 10% of patients with OHS have non-obstructive sleep hypoventilation without OSA or with mild OSA. This review aims to provide a comprehensive understanding of the epidemiological and pathophysiological impact of OHS and to highlight its clinical features, prognosis, and severity, as well as the available treatment options.